2020 Cilt 18 Sayı 1

Permanent URI for this collectionhttps://hdl.handle.net/11452/12714

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Browsing by BUU Author "Varal, İpek Günay"

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    Outcomes of inhaled nitric oxide in preterm and term infants: A four-year experience in a tertiary neonatal unit
    (Bursa Uludağ Üniversitesi, 2020-01-16) Varal, İpek Günay; Doğan, Pelin
    This study aimed at assessing the data of term and preterm neonates with pulmonary hypertension (PH) to characterise patients and the effectiveness of inhaled nitric oxide (iNO). The study cohort treated with iNO between 2015 and 2019 was categorized into two groups according to the gestational age (GA) and timing of PH. Overall 56 neonates were enrolled. Pre-iNO, post-iNO mean airway pressure values, and oxygenation index were significantly higher in the preterm group (p < 0.05). Mean GA and birth weight of the infants who had early PH diagnosis were higher. Positive responders were more likely to have higher GA as well as higher birth weight (p < 0.05). Non-responders were mostly diagnosed with diaphragmatic hernia in term infants and with sepsis in preterm infants. Despite term infants have higher positive response rate to treatment, initiating early treatment will increase the rate of positive response in preterm infants.