Browsing by Author "Alkan, Feray"
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Item Course and severity of postpartum metritis cases following antibiotic and PGF2α administration in postpartum metritis cows infected with BoHV-4(Wiley, 2011-02) Bilge, Seval Dağalp; Alkan, Feray; Nak, Yavuz; Çetin, Cengiz; Nak, Deniz; Borum, Ebru; Tuna, Bilginer; Uludağ Üniversitesi/Veterinerlik Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı.; Uludağ Üniversitesi/Veterinerlik Fakültesi/Mikrobiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Keleş Meslek Yüksek Okulu/Hayvancılık ve Süt Ürünleri Bölümü.; 0000-0002-1166-721X; AAH-5494-2021; ABE-5581-2021; 8615464000; 7003489234; 9280090000; 36738850800; 9280090300Forty cows between day 1 and day 21 post-calving were examined for the presence of postpartum metritis in a dairy herd that had recently experienced an increase in metritis and that had previously tested positive against bovine herpes virus 4 (BoHV-4) by various methods. Antibodies against BoHV-4 were detected in sera from 15 of 22 cows. For the virological study, uterine swab samples of 22 cows with metritis were used and tested for BoHV-4 using polymerase chain reaction (PCR), virus isolation (VI), and immunofluorescence techniques. Twenty-two point seven per cent (5/22) of the vaginal discharge samples obtained from cows with metritis were found positive for BoHV-4 DNA by PCR. All of these samples were also positive in VI and/or immune fluorescence assay (IF). Swab samples were also tested for bacteria. Empirical therapy with a broad spectrum antibiotic (oxytetracycline) was administrated, pending culture and antibiotic sensitivity result. All cows with puerperal metritis or clinical metritis (CM) were treated with intra-uterine (i.u.) administration of oxytetracycline and with intramuscular (i.m.) injections of dinoprost tromethamine (PGF(2)alpha) for three consecutive days. Concurrently, with the administration of oxytetracycline and PGF(2)alpha, cows with a rectal temperature >39.5 degrees C received an additional treatment with oxytetracycline (i.m) for three consecutive days. According to the antibiotic test result, on day 3 after the last oxytetracycline and PGF(2)alpha administrations, all cows were treated with a combination of amoxicillin and clavulanic acid (i.u.) for three consecutive days. All cows with metritis and that were positive for BoHV-4 recovered clinically after the administration of antibiotic and PGF(2)alpha. In conclusion, postpartum metritis cases in cows infected BoHV-4 recovered clinically following early diagnosis and prolonged treatments with a combination of antibiotics and PGF(2)alpha.Item The seroprevalence of BHV-1 infection on selected dairy cattle herds in Turkey(Ecole Nationale Veterinaire Toulouse, 2005-03) Alkan, Feray; Burgu, İbrahim; Bilge-Dağalp, Seval; Yıldırım, Yasemin; Gençay, Ayşe; Ataseven, Veysel Soydan; Akca, Yılmaz; Güngör, Burak H.; Uludağ Üniversitesi/Veteriner Fakültesi.; 24343387200In this study, serum samples of 13011 cattle from 31 dairy herds located in various regions of Turkey were tested for presence of neutralising antibodies against BHVI using the serum neutralisation (SN) technique. It was found that 97% (30/31) of the herds selected had seropositive animals and the frequencies of seropositivity were between 0.5-79.5% in the surveyed herds. Furthermore, recommendations to the control and eradication programme of the BHV1 infection were presented.