Browsing by Author "Andrieu, Meltem Nalca"

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    A case report of primary breast angiosarcoma: Clinical presentation and outcome after adjuvant radiotherapy
    (Aves, 2020-10-01) Altmisdörtoğlu, Özgür; Andrieu, Meltem Nalca; Gökgöz, Mustafa Şehsuvar; GÖKGÖZ, MUSTAFA ŞEHSUVAR; Yalçınkaya, Ulviye; YALÇINKAYA, ÜLVİYE; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Genel Cerrahi Anabilim Dalı.; AAH-8924-2021
    Angiosarcomas of the breast are infrequent subtypes of sarcoma that are often diagnosed after radiation therapy for primary breast cancer. Primary angiosarcomas (PAS) are rare tumors that constitute 0.04% of all malignant breast tumors. We report a case of a 40-year-old woman with a lump in the right breast and diagnosed as angiosarcoma by pathological evaluation. She underwent simple mastectomy followed by adjuvant radiation. She is alive and disease-free for 66 months although tumor size was large and one surgical margin was tumor positive. Breast angiosarcoma is often in advanced stage at diagnosis and tends to recur locally. Although surgical methods constitute the primary treatment, we believe that a multidisciplinary treatment strategy should be used in high-risk patients with large primary tumors and tumor positive margins.
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    Patterns of care for lung cancer in radiation oncology departments of Turkey
    (Elsevier Science Inc, 2008-12-01) Demiral, Ayse Nur; Alıcıkus, Zümre Arıcan; Uğur, Vahide Isıl; Karadoğan, İlker; Yöney, Adnan; Andrieu, Meltem Nalca; Yalman, Deniz; Pak, Yücel; Aksu, Gamze; Özyiğit, Gökhan; Kılçıksız, Sevil; Koca, Sedat; Çaloğlu, Murat; Yavuz, Ali Aydın; Çağlar, Hale Basak; Beyzadeoğlu, Murat; Çigdem, Sefik; Serin, Meltem; Kaplan, Bünyamin; Koç, Mehmet; Korkmaz, Esra; Karakoyun-Çelik, Ömer; Dinçer, Selvi; Kınay, Münir; Özkan, Lütfi; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı.; 0000-0003-0388-676X; 0000-0002-5445-6797; 0000-0001-7897-8445; 0000-0002-7497-4348; 0000-0002-1433-8403; 0000-0002-6181-3254; B-3319-2008; AAM-1051-2020; Q-2364-2015; Q-2090-2019; C-3154-2016; Q-1619-2019; I-9471-2013; ABG-5077-2020; ABI-5084-2020; C-2284-2016; Y-7790-2018
    Purpose: To determine the patterns of care for lung cancer in Turkish radiation oncology centers.Methods and Materials: Questionnaire forms from 21 of 24 (87.5%) centers that responded were evaluated.Results: The most frequent histology was non-small cell lung cancer (NSCLC) (81%). The most common postoperative radiotherapy (RT) indications were close/(+) surgical margins (95%) and presence of pN2 disease (91%). The most common indications for postoperative chemotherapy (CHT) were ">= IB" disease (19%) and the presence of pN2 disease (19%). In Stage IIIA potentially resectable NSCLC, the most frequent treatment approach was neoadjuvant concomitant chemoradiotherapy (CHRT) (57%). In Stage IIIA unresectable and Stage IIIB disease, the most frequent approach was definitive concomitant CHRT (91%). In limited SCLC, the most common treatment approach was concomitant CHRT with cisplatin+etoposide for cycles 1-3, completion of CHT to cycles 4-6, and finally prophylactic cranial irradiation in patients with complete response (71%). Six cycles of cisplatin + etoposide CHT and palliative thoracic RT, when required, was the most commonly used treatment (81%) in extensive SCLC. Sixty-two percent of centers did not have endobronchial brachytherapy (EBB) facilities.Conclusion: There is great variation in diagnostic testing, treatment strategies, indications for postoperative RT and CHT, RT features, and EBB availability for LC cases. To establish standards, national guidelines should be prepared using a multidisciplinary approach.