Browsing by Author "Bayram, Sami"

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Bronchopulmonary sequestration: Radiologic findings
(Elsevier Ireland, 2004-11) Bolca, Naile; Topal, Uğur; Bayram, Sami; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Kalp ve Damar Cerrahisi Anabilim Dalı.; 23569259700; 57001254100; 8705640100
Bronchopulmonary sequestration (BPS) is a nonfunctioning bronchopulmonary tissue that is separate from the tracheobronchial tree and receives arterial blood from the systemic circulation. BPS has a wide spectrum of imaging findings. Surgery is generally indicated for the treatment of BPS. It is important to demonstrate the arterial supply and venous drainage of the sequestered segment preoperatively. Today, with the help of noninvasive imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI), preoperative diagnosis of BPS can be made easily, so, invasive techniques such as angiography are not required frequently. In this report, radiological findings of BPS were retrospectively reviewed.
Cisplatin plus etoposide in the adjuvant treatment of patients with non small cell lung cancer
(Derman Medical Publ, 2014-09-01) Çubukcu, Erdem; Canhoroz, Mustafa; Ölmez, Ömer Fatih; Kanat, Özkan; Kurt, Ender; Erol, Muharrem; Çubukcu, Sinem; Yorulmaz, Nadide; Bayram, Sami; Evrensel, Türkkan; Manavoğlu, Osman; ÇUBUKÇU, ERDEM; Canhoroz, Mustafa; Ölmez, Ömer Fatih; Kanat, Özkan; Kurt, Ender; Erol, Muharrem; ÇUBUKÇU, SİNEM; Yorulmaz, Nadide; BAYRAM, AHMET SAMİ; EVRENSEL, TÜRKKAN; Manavoğlu, Osman; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Onkoloji Anabilim Dalı.; 0000-0002-9732-5340; JGT-4101-2023; CJW-6018-2022; DJG-4827-2022; CYM-0930-2022; DAS-3088-2022; JEN-3243-2023; JJB-0254-2023; GKI-1183-2022; EMY-5874-2022; AAJ-1027-2021; FLP-9613-2022
Aim: In this study, the efficacy and safety of cisplatin and etoposide (PE) combination in the adjuvant treatment of patients with resected non-small cell lung cancer (NSCLC) was investigated. Material and Method: We retrospectively evaluated the medical charts of patients receiving adjuvant treatment for NSCLC at our center. Results: Forty-five patients were evaluated. The disease-free survival was 10 (1-114) months and the median overall survival was 18 (3-114) months. Discussion: Based on our limited experience, we concluded that PE regimen is safe and effective as adjuvant therapy for patients with NSCLC.
Comparison of lumbar epidural tramadol and lumbar epidural morphine for pain relief after thoracotomy: A repeated-dose study
(W B Saunders Co-Elsevier Inc, 2005-08) Türker, Gürkan; Gören, Suna; Bayram, Sami; Şahin, Şükran; Korfalı, Gülsen; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; 0000-0002-1190-6831; 0000-0002-3019-581X; AAI-6642-2021; AAI-3551-2021
Objective: The purpose of this study was to compare lumbar epidural morphine and lumbar epidural tramadol with respect to onset and duration of analgesia, analgesic efficacy, and drug-related side effects after muscle-sparing thoracotomy. Design: Prospective, randomized, double-blind, clinical study. Setting: Single university hospital. Participants: Forty patients who underwent elective muscle-sparing thoracotomy. Interventions: Before anesthesia induction, an epidural catheter was placed in the L2-3 or L3-4 interspace using the loss-of-resistance technique. On arrival at the intensive care unit, patients were randomized to receive doses of either 100 mg of tramadol (group T) or 4 mg of morphine (group M) via the lumbar epidural catheter. Each dose was diluted in 10 mL of normal saline. On awakening from anesthesia, if the patient's pain score on a 0- to 100-mm visual analog scale was above 40 mm, the initial epidural drug dose was administered. The initial injection in each case was taken as time 0. Subsequent pain scores above 40 mm were considered indications for epidural dosing; each patient was allowed 2 doses in the first 12 hours postoperatively and 2 more in the second 12 hours. Measurements and Main Results: The groups' analgesia onset times were similar, but duration of analgesia was significantly shorter in group T than in group M (p < 0.01). There were no differences between the groups with respect to pain scores at rest or during coughing at any of the time points investigated. Sedation scores were lower in group T than in group M at 1, 2, 3, 4, and 8 hours (p value range, 0.0001-0.05). Compared with group T, group M showed significantly greater drops in arterial oxygen tension from baseline at 3, 4, 8, and 12 hours (p value range, 0.0001-0.05). The group means for arterial carbon dioxide tension and respiratory rate were similar at all time points investigated. Conclusion: The study revealed that the quality of analgesia achieved with repeated doses of lumbar epidural tramadol after muscle-sparing thoracotomy is comparable to that achieved with repeated doses of lumbar epidural morphine. Compared with morphine, lumbar epidural tramadol results in less sedation and a less-pronounced decrease in oxygenation.
Evaluation of a clinical pulmonary infection score in the diagnosis of ventilator-associated pneumonia
(Mre Press, 2012-04) Güler, Emre; Kahveci, Ferda; Akalın, Halis; Sınırtaş, Melda; Bayram, Sami; Özcan, Berin; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji ve Enfeksiyon Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; 0000-0003-4820-2288; AAG-9356-2021; AAU-8952-2020; 57198133515; 6602405968; 57207553671; 6505818048; 8705640100; 6603825848
The most important dilemma in the diagnosis of ventilator-associated pneumonia (VAP) based on only clinical findings is overdiagnosis. The aim of the study is to prospectively evaluate the Clinical Pulmonary Infection Score (CPIS) in relation to VAP diagnosis. Design. Prospective, in a cohort of mechanically ventilated patients. Setting. The intensive care unit of a university hospital. Patients. Fifty patients, on mechanical ventilation therapy for more than 48 hours, suspected of having VAP were enrolled in the study and bacteriologic confirmation was done by bronchoalveolar lavage (BAL) culture. Interventions. Bronchoscopy with BAL fluid culture after establishing a clinical suspicion of VAP in patients having no prior antibiotic therapy or no change in current antibiotic therapy within last three days before BAL. CPIS scores during diagnosis were 6+/-2 (3-9) (median+/-QR, maximum-minimum) and it was 7+/-2 (2-9) at the 72nd hour, in 41 cases with a diagnosis of VAP. In cases with no diagnosis of VAP, the CPIS scores were found to be 6+/-2 (4-8) and 5+/-3 (2-7), respectively. There was no significant difference between the VAP group and the non-VAP group at diagnosis, but was significant at 72nd hour (respectively, p=0.551 and p=0.025). CPIS scores during diagnosis were 6+/-3 (4-8) (median+/-QR, maximum-minimum) and 7+/-4 (2-8) at the 72nd hour, in 14 cases with a diagnosis of early-onset VAP. In cases with a diagnosis of late-onset VAP, the CPIS scores were found to be 6+/-2 (3-9) and 7+/-2 (3-9), respectively. There was no significant difference between the early-onset VAP group and the late-onset VAP group. In conclusion, the CPIS results should be evaluated carefully in the clinical setting during the diagnosis.
Evaluation of polylactide film for prevention of pericardial adhesion in a rabbit model
(Baycinar Medical Publ-Bayçınar Tıbbi Yayıncılık, 2015-01-01) Gürbüz, Orçun; Ercan, Abdulkadir; Biçer, Murat; Kumtepe, Gencehan; Bayram, Sami; Şenkaya, Işık; Saba, Davit; BİÇER, MURAT; BAYRAM, AHMET SAMİ; ŞENKAYA SIĞNAK, IŞIK; Saba, Davit; Uludağ Üniversitesi/Tıp Fakültesi/Kalp Damar Cerrahisi Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; ABC-2231-2020; ABB-7580-2020; DTC-2331-2022; DPS-9311-2022
Background: This study aims to evaluate the efficacy of a bioabsorbable polylactide film, which was proven to be effective in preventing pelvic adhesions, in prevention of postoperative pericardial adhesions in an animal model.Methods: Forty New Zealand white rabbits were divided equally into control and treatment groups. Subjects were performed left anterior thoracotomy and partial pericardiectomy followed by epicardial abrasion. In control groups (group 1 and 2), the pericardium was left open to allow retrosternal adhesions. In treatment groups (group 3 and 4), the pericardial defect was closed with 0.02 mm bioabsorbable polylactide film. Postoperative macroscopic and microscopic evaluations were made by the same blinded observers at the end of the third week in group 1 and 3, and at the end of the sixth week in group 2 and 4.Results: Macroscopic and histopathologic examinations revealed no significant differences between control and treatment groups in terms of adhesion formation. However, polylactide film supported the growth of a mesothelium-like layer in the treatment groups.Conclusion: Although polylactide film assists in the regeneration of mesothelial cells layer, it does not prevent the development of pericardial adhesions.
İntravenöz parasetamolün torakoskopik cerrahi sonrası postoperatif analjezi üzerine etkinliği
(Uludağ Üniversitesi, 2010-05-07) Çınar, Vildan; Kaya, Fatma Nur; Yavaşçaoğlu, Belgin; Gören, Suna; Bayram, Sami; Moğol, Elif Başağan; Kaya, Atilla; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.
Çalışmamızda, torakoskopik cerrahi sonrası intravenöz parasetamol uygulamasının postoperatif analjezi üzerine etkinliğini değerlendirmeyi amaçladık. ASA I-II grubu 40 hasta, anestezi indüksiyonundan önce ve postoperatif 24 saat içinde her 6 saatte bir intravenöz 1 gr parasetamol veya 100 ml serum fizyolojik verilmek üzere randomize olarak ayrıldı. Dinlenme ve hareket sırasındaki ağrı skorları, sedasyon skorları, hemodinamik parametreler, morfin kullanımı, hasta/hemşire memnuniyeti ve yan etkiler değerlendirildi. İlk analjezik gereksinim zamanı, ilk mobilizasyon ve hastaneden çıkış zamanları kaydedildi. Parasetamol grubunda; morfin tüketimi postoperatif 2., 4., 8., 12. ve 24. saatlerde daha düşük (p=0.017, p=0.021, p<0.001, p<0.001, p<0.001), bulantı ve kusma sıklığı daha az (p=0.001, p<0.001); ilk analjezi gereksinim zamanı daha uzun (p=0.0032), ilk mobilizasyon ve hastaneden çıkış süreleri daha kısa bulundu (p=0.0031, p=0.0015). Analjezi açısından hasta/hemşire memnuniyeti anlamlı olarak fazlaydı (p<0.001, p<0.001). Sonuç olarak, parasetamol kullanımı daha az yan etki ile postoperatif morfin gereksinimini azalttı ve hasta/hemşire memnuniyetini artırdı. Bu yaklaşım torakoskopik cerrahi sonrası erken postoperatif mobilizasyona da katkıda bulunabilir.
Preoperative multiple-injection thoracic paravertebral blocks reduce postoperative pain and analgesic requirements after video-assisted thoracic surgery
(Elsevier, 2006) Kaya, Fatma Nur; Türker, Gürkan; Başağan, Moğol, Elif; Gören, Suna; Bayram, Sami; Gebitekin, Cengiz; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; 0000-0002-3019-581X; AAI-6642-2021; AAI-8213-2021
Objective: The hypothesis was tested that preoperative multiple-injection thoracic paravertebral blocks reduce opioid requirements and promote early ambulation after video-assisted thoracic surgery procedures. Design: Prospective, randomized, controlled, blinded study. Setting: Single-university hospital. Participants: Fifty consenting patients undergoing video-assisted thoracic surgery. Interventions: Patients were randomly assigned to receive preoperative multiple-injection thoracic paravertebral blocks (PVB group, n = 25) or preoperative multiple subcutaneous saline injections at the same site as in the PVB group (control group, n = 25). Measurements and Main Results: Intraoperative fentanyl consumption was lower in the PVB group (p < 0.01). The time to first analgesic requirement was longer, and pain score at this time was lower in the PVB group (p < 0.05 and p < 0.01, respectively). Postoperative pain scores both at rest and coughing were lower during the first 4 hours in the PVB group than those in the control group (p < 0.01 for 0 hours and p < 0.05 for 1, 2, and 4 hours). Cumulative morphine consumption was significantly less in the PVB group at all time points (p < 0.05 for 12 hours and p < 0.01 for all other time points), but there were no significant differences in sedation scores between the 2 groups. There were no complications because of the blocks. Patient satisfaction with the analgesia was significantly greater (p < 0.05), and first mobilization and hospital discharge were quicker (p < 0.01 and p < 0.05, respectively) in the PVB group. Conclusion: Perioperative multiple-injection'thoracic paravertebral blocks with bupivacaine containing epinephrine provided effective pain relief and a significant reduction in opioid requirements. This approach may also contribute to earlier postoperative ambulation after video-assisted thoracic surgery.
Pulmonary sclerosing hemangioma exhibiting a high KI-67 proliferation index
(Erciyes Üniversitesi, 2012-04-17) Akyıldız, Elif Ülker; Bayram, Sami; Arıcı, Akgül; Kasap, Mehtap; AKYILDIZ, ELİF ÜLKER; BAYRAM, AHMET SAMİ; Arıcı, Akgül; Kasap, Mehtap; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Torasik Cerrahi Anabilim Dalı.; ABB-7580-2020; JHY-9777-2023; EKW-8583-2022; FDC-3047-2022
Pulmonary sclerosing hemangioma (PSH) is a rare pulmonary neoplasm. This tumour was originally thought to be a variant lesion of hemangioma. Today, however, it has been elucidated to be a tumour of epithelial origin derived from the primitive respiratory epithelium. Previous studies have reported a low Ki67 proliferation index in cases of pulmonary sclerosing hemangioma (1.4-2.2%). Moreover, the biological nature of this neoplasm, which rarely tends to metastasise to the lymph nodes, has yet to be thoroughly elucidated. A female patient in whom PSH exhibiting a high Ki-67 proliferation index was detected in the lung during follow-up for lymphoma is reported in the present study. While the Ki 67 proliferation index was 3-4% in some areas, it increased up to 15-20% in other areas. No recurrence or metastases were evident at postoperative follow-up.
Pulmoner arter sarkomu
(Uludağ Üniversitesi, 2003-04-21) Topal, Uğur; Yurtsever, İsmail; Yerci, Ömer; Bayram, Sami; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.
Pulmoner arter sarkomları nadir görülür. Klinik ve radyolojik bulguların özgün olmaması nedeniyle genellikle tanı ameliyat sırasında veya otopsilerde konur. Hemoptizi yakınmasıyla araştırılan 53 yaşında erkek olgunun göğüs röntgenogramlarında ve BT incelemesinde sağ akciğer hilusunda kitle ve akciğerde nodül saptandı. BT eşliğinde transtorasik iğne biyopsisi yapılarak pulmoner arter sarkomu tanısı kondu. Bu yazıda, olgumuzun klinik ve radyolojik bulguları literatür verileri ışığında sunulmuştur.