Browsing by Author "Engin, B."

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Clinical and demographic features of hidradenitis suppurativa: A multicentre study of 1221 patients with an analysis of risk factors associated with disease severity
(Wiley, 2021-01-02) Ozkur, E.; Karadag, A. S.; Ustuner, P.; Aksoy, B.; Esme, P.; Caliskan, E.; Akoglu, G.; Kalkan, G.; Demirseren, D. D.; Polat, M.; Ozden, M. G.; Kilinc, F.; Yalcinkaya Iyidal, A.; Kivanc Altunay, I.; Turkmen, M.; Ugurer, E.; Baysak, S.; Fettahlioglu Karaman, B.; Mammadli, K.; Baykal Selcuk, L.; Turkoglu, Z.; Atci, T.; Didar Balci, D.; Adisen, E.; Temel, B.; Aktan, S.; Kacar, N.; Gunduz, K.; Turel Ertmertcan, A.; Ozdemir, M.; Cakiter, A. Unal; Colgecen, E.; Ucmak, D.; Kelekci, H.; Ataseven, A.; Durmaz, K.; Kaya Ozden, H.; Engin, B.; Yazici, S.; Alpsoy, E.; Yazici, S.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.; 0000-0002-9136-7021; 0000-0002-2358-7938; 0000-0002-4480-7792; 0000-0001-9137-2675; 0000-0002-1354-7123; 0000-0002-7003-0390; 0000-0003-4236-0066; 0000-0001-7956-4033; 0000-0001-5528-9006; 0000-0002-0201-4663; 0000-0002-1156-2776; 0000-0002-4119-9939; 0000-0003-0203-272X; 0000-0001-6407-0962; 0000-0001-7049-0170; HLQ-7709-2023; AAA-7871-2022; AGU-8205-2022; GQZ-6475-2022; AAS-9706-2020; IVH-1591-2023; HGE-4978-2022; E-7490-2016; C-1183-2016; V-7974-2018; V-6081-2017; AAE-4622-2021; ABD-6477-2022; AGK-5823-2022
Background Hidradenitis suppurativa (HS) is a chronic, relapsing and debilitating inflammatory disease associated with profound morbidity.Aim In this multicentre study, we investigated the demographic and clinical features of HS, and determined risk factors of disease severity.Methods In total, 1221 patients diagnosed with HS from 29 centres were enrolled, and the medical records of each patient were reviewed.Results The mean age of disease onset was 26.2 +/- 10.4 years, and almost 70% (n = 849) of patients were current or former smokers. Mean disease duration was 8.9 +/- 8.4 years with a delay in diagnosis of 5.8 +/- 3.91 years. Just over a fifth (21%; n = 256) of patients had a family history of HS. The axillary, genital and neck regions were more frequently affected in men than in women, and the inframammary region was more frequently affected in women than in men (P < 0.05 for all). Acne (40.8%), pilonidal sinus (23.6%) and diabetes mellitus (12.6%) were the most prevalent associated diseases. Of the various therapies used, antibiotics (76.4%) were most common followed by retinoids (41.7%), surgical interventions (32.0%) and biologic agents (15.4%). Logistic regression analysis revealed that the most important determinants of disease severity were male sex (OR = 2.21) and involvement of the genitals (OR = 3.39) and inguinal region (OR = 2.25). More severe disease was associated with comorbidity, longer disease duration, longer diagnosis delay and a higher number of smoking pack-years.Conclusions Our nationwide cohort study found demographic and clinical variation in HS, which may help broaden the understanding of HS and factors associated with disease severity.
Effects of rim thickness on tooth root stress and mesh stiffness of internal gears
(Amer Soc Mechanical Engineers, 2015-01-01) Yilmaz, Tufan; YILMAZ, TUFAN GÜRKAN; Yüce, Celalettin; YÜCE, CELALETTİN; Karpat, Fatih; KARPAT, FATİH; Engin, B.; Doğan, O.; DOĞAN, OĞUZ; Bursa Uludağ Üniversitesi/Mühendislik Fakültesi/Makine Mühendisliği Bölümü.; 0000-0001-8474-7328; 0000-0003-4203-8237; 0000-0003-1387-907X; 0000-0003-3772-7871; A-5259-2018; GXH-1702-2022; R-3733-2017; AAV-7897-2020; V-6153-2017
In recent years, internal gears are used commonly in a number of automotive and aerospace applications especially in planetary gear drives. Planetary gears have many advantages such as compactness, large torque-to-weight ratio, large transmission ratios, reduced noise and vibrations. Although internal gears have many advantages, there are not enough studies on it. Designing an internal gear mechanism includes two important parameters. The gear mesh stiffness which is the main excitation source of the system. In this paper, 2D gear models are developed in order to compute gear mesh stiffness for various rim thicknesses and different rim shapes of the internal gear design. Effects of root stress with varying rim thickness and some tooth parameters are investigated by using 2D gear models. The stress calculated according to ISO 6336 and the stresses calculated against FEM are compared. These results are well-matched. It is observed that when the rim thicknesses are increased, both the maximum bending stresses and gear mesh stiffness are decreased considerably.
Instruments for screening psoriatic arthritis among patients with psoriasis: A systematic literature review
(Bmj Publishing Group, 2021-06-01) Can, G.; Ayan, G.; Ozdede, A.; Bektas, M.; Akdogan, N.; Yalici-Armagan, B.; Solak, E. Oksum; Kalyoncu, U.; Adisen, E. Ozsoy; Atakan, N.; Borlu, M.; Engin, B.; Hamuryudan, V.; Inanc, M.; Kiraz, S.; Onen, F.; Ugurlu, S.; Yayli, S.; Hatemi, G.; Yazici, S.; Baskan, E. Bulbul; BÜLBÜL BAŞKAN, EMEL; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.