Browsing by Author "Telli, Murat"

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    Antimicrobial resistance in Gram-negative hospital isolates: Results of the Turkish HITIT-2 surveillance study of 2007
    (Taylor & Francis, 2009-08) Gür, Deniz; Hasçelik, Ayşe Gülşen; Aydın, Neriman; Telli, Murat; Gültekin, Meral; Ogünç, Dilara; Arıkan, Osman Atilla; Uysal, Sevil; Yaman, Akgün; Kibar, Filiz; Gülay, Zeynep; Sümerkan, Bülent; Esel, Duygu; Kayacan, Ciğdem; Aktaş, Zerrin; Söyletir, Güner; Altınkanat, Gülşen; Durupınar, Belma; Darka, Özge; Akgün, Yurdanur; Yayla, Buket; Berktaş, Mustafa; Yaman, Görkem; Gedikoğlu, Suna; Sinirtaş, Melda; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji Anabilim Dalı.; 6603407548; 6505818048
    Resistance rates to amikacin, ciprofloxacin, ceftazidime, cefepime, imipenem, cefoperazone/sulbactam and piperacillin/tazobactam in Escherichia coli (n = 438), Klebsiella pneumoniae (n = 444), Pseudomonas aeruginosa (n = 210) and Acinetobacter baumanni (n =200) were determined with E-test in a multicenter surveillance study (HITIT-2) in 2007. ESBL production in Escherichia coli and K. pneumoniae was investigated following the CLSI guidelines. Overall 42.0% of E.coli and 41.4% of K. pneumoniae were ESBL producers. In E. coli, resistance to imipenem was not observed, resistance to ciprofloxacin and amikacin was 58.0% and 5.5% respectively. In K. pneumoniae resistance to imipenem, ciprofloxacin and amikacin was 3.1%, 17.8% 12.4% respectively. In P. aeruginosa the lowest rate of resistance was observed with piperacillin/tazobactam (18.1%). A. baumanni isolates were highly resistant to all the antimicrobial agents, the lowest level of resistance was observed against cefoperazone/sulbactam (52.0%) followed by imipenem (55.5%). This study showed that resistance rates to antimicrobials are high in nosocomial isolates and show variations among the centers.
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    The presence of Campylobacter jejuni in broiler houses: Results of a longitudinal study
    (Academic Journals, 2011-02-18) Çokal, Yavuz; Telli, Murat; Şen, Ayşin; Çetin, Cengiz; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji Anabilim Dalı.; 0000-0002-9212-8743; AAH-1820-2021
    In this study, the presence of Campylobacter jejuni in water lines of commercial broiler house and its role in the epidemiology of the infection of broiler flocks was investigated. The study was done in three sequential commercial broiler flocks previously known to be infected with C. jejuni in two poultry houses with different water sources. C. jejuni was identified in drinking water and drinking nipple swab samples in water-line samples from both houses. Fresh fecal dropping samples were taken from broiler flocks for determination of C. jejuni-carriage. Twenty and 130 C. jejuni isolates were recovered from water-line system and fecal dropping samples, respectively. A total of 150 C. jejuni isolates were genotyped by pulsed-field gel electrophoresis (PFGE) with SmaI digestion and 9 distinct PFGE patterns were identified. Six and 5 different PFGE types were identified in houses 1 and 2, respectively. C. jejuni isolates, recovered from water lines samples, were genotypically similar to the isolates from fresh fecal dropping in both houses. These results showed that C. jejuni water-line contamination was related to flock contamination and could help to continuously make it infected with C. jejuni.