Browsing by Author "Toker, Rabia Tutuncu"
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Publication Etiology, clinic and prognosis of seizures in preterm and term neonates: A retrospective study(Bursa Uludag Üniversitesi, 2021-08-01) Cakir, Salih Cagri; ÇAKIR, SALİH ÇAĞRI; Toker, Rabia Tutuncu; TÜTÜNCÜ TOKER, RABİA; Koksal, Nilgun; Ozkan, Hilal; ÖZKAN, HİLAL; Okan, Mehmet Sait; OKAN, MEHMET SAİT; Kocael, Fatma; KOCAEL, FATMA; Yoruk, Gulce; YÖRÜK, GÜLCE; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dali; 0000-0001-5761-4757; 0000-0002-3129-334X; 0000-0002-9303-5768; 0000-0002-1787-6872; IZP-6290-2023; HJZ-4508-2023Introduction: The seizure is one of the most common neurological problems in neonatal intensive care units (NICU). Its frequency and etiology differ between preteen and term babies. This study aimed to investigate the properties, causes, response to treatment, and prognostic factors of neonatal seizures in term and preterm babies.Materials and Methods: The files of patients with a diagnosis of neonatal seizure in the NICU between 01/01/2014 and 01/09/2019 were analyzed retrospectively. Gross motor function classification, hearing test results and epilepsy rates were examined for neurological outcomes.Results: A total of 86 patients (43 preterm and 43 term infants) were included in this study. The most common etiological factors were hypoxic-ischemic encephalopathy (HIE) (35%) in term infants and intraventricular hemorrhage (IVH) in preterm infants (54%). The most common seizure type was subtle seizures in preterm babies and clonic seizures in term babies. The first seizure day was more on the first day and between the 4-7 days in term babies and after seventh days in preterm babies (p <0.05). The onset time of seizures in preterm babies was more after seven days at IVH, and on the first day at HIE (p<0.05). Status epilepticus frequency is higher in preterm (30%) than term (9.3%) (p = 0.015). The response rate to phenobarbital treatment was 71% in term infants and 50% in preterm infants (p = 0.06). According to the criteria (death, epilepsy, hearing loss, autism and gross motor function scale> 2) in our study, the poor prognosis rates were (52%) in term infants and (75%) in preterm infants (p = 0.051).Conclusion: In the etiology of neonatal seizures, IVH in preterm infants and HIE in term infants were the first. The neurological outcomes of patients who had convulsions in the neonatal period should be followed closely.Publication Evaluation of patients admitted to pediatric emergency outpatient clinic with non-traumatic neurological complaint(Bursa Uludag Univ, 2020-12-01) Toker, Rabia Tutuncu; TÜTÜNCÜ TOKER, RABİA; Bodur, Muhittin; BODUR, MUHİTTİN; Özmen, Abdullah Hakan; ÖZMEN, ABDULLAH HAKAN; Okan, Mehmet Sait; OKAN, MEHMET SAİT; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.; 0000-0002-3129-334X; 0000-0002-2588-8195; 0000-0002-9303-5768; JAN-9435-2023; AAH-2684-2021; AAE-2163-2022; IZP-6290-2023; AAF-8981-2020INTRODUCTION: Pediatric Emergency Outpatient Clinic are the units where treated the entire range of emergent and urgent medical conditions. Patients present with a wide range of complaints. Determining the general distribution, frequency and density of Pediatric Emergency Outpatient Clinic applications is of great importance in order to make appropriate future plans. In this study, it was aimed to evaluate the clinical features of patients presenting with non-traumatic neurological complaints.MATERIALS and METHODS: The files of the patients who applied to the Pediatric Emergency Outpatient Clinic within one year were evaluated retrospectively. Patients with a known neurological disease who presented to the Pediatric Emergency Outpatient clinic with non neurological complaints, those in the neonatal and trauma patients were not included in the study.RESULTS: It was found that the main complaint of 628 of the patients who applied to the Pediatric Emergency Outpatient Clinic within a year was neurological symptoms. % 50,3 of the patients were found as girls and %49,7 as boys. Seizure was the most common neurological complaint. It was found that %83,1 of the patients who presented with seizures for the first time presented with a febrile seizures and %16,9 with febrile seizures. Status epilepticus rate was found to be %4,5 in patients presenting with seizuresCONCLUSIONS: Seizure was the most common non-traumatic neurological presentation to Pediatric Emergency Outpatient Clinic. We believe that updating knowledge and skills on emergency approach to seizures in Pediatric Emergency Outpatient Clinic will increase the quality of healthcare services to be provided.