Browsing by Author "Uysal, Sevil"

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    Antimicrobial resistance in Gram-negative hospital isolates: Results of the Turkish HITIT-2 surveillance study of 2007
    (Taylor & Francis, 2009-08) Gür, Deniz; Hasçelik, Ayşe Gülşen; Aydın, Neriman; Telli, Murat; Gültekin, Meral; Ogünç, Dilara; Arıkan, Osman Atilla; Uysal, Sevil; Yaman, Akgün; Kibar, Filiz; Gülay, Zeynep; Sümerkan, Bülent; Esel, Duygu; Kayacan, Ciğdem; Aktaş, Zerrin; Söyletir, Güner; Altınkanat, Gülşen; Durupınar, Belma; Darka, Özge; Akgün, Yurdanur; Yayla, Buket; Berktaş, Mustafa; Yaman, Görkem; Gedikoğlu, Suna; Sinirtaş, Melda; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji Anabilim Dalı.; 6603407548; 6505818048
    Resistance rates to amikacin, ciprofloxacin, ceftazidime, cefepime, imipenem, cefoperazone/sulbactam and piperacillin/tazobactam in Escherichia coli (n = 438), Klebsiella pneumoniae (n = 444), Pseudomonas aeruginosa (n = 210) and Acinetobacter baumanni (n =200) were determined with E-test in a multicenter surveillance study (HITIT-2) in 2007. ESBL production in Escherichia coli and K. pneumoniae was investigated following the CLSI guidelines. Overall 42.0% of E.coli and 41.4% of K. pneumoniae were ESBL producers. In E. coli, resistance to imipenem was not observed, resistance to ciprofloxacin and amikacin was 58.0% and 5.5% respectively. In K. pneumoniae resistance to imipenem, ciprofloxacin and amikacin was 3.1%, 17.8% 12.4% respectively. In P. aeruginosa the lowest rate of resistance was observed with piperacillin/tazobactam (18.1%). A. baumanni isolates were highly resistant to all the antimicrobial agents, the lowest level of resistance was observed against cefoperazone/sulbactam (52.0%) followed by imipenem (55.5%). This study showed that resistance rates to antimicrobials are high in nosocomial isolates and show variations among the centers.