Browsing by Author "Uzuner, Nevin"

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Characteristics and prognosis of childhood atopic dermatitis: A multi-center study in Turkey
(Wiley, 2009) Yüksel, Hasan; Can, Demet; Reisli, İsmail; Uzuner, Nevin; Orhan, Fazıl; Cevit, Ömer; Tahan, Fulya; Kuyucu, Semanur; Boz, Bingol A.; Akçay, Ahmet Oğuz; Yılmaz, Özge; Canıtez, Yakup; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.
Characteristics and prognosis of childhood atopic dermatitis: A multicenter study in Turkey
(Karger, 2010) Yüksel, Hasan; Can, Demet; Reisli, İsmail; Uzuner, Nevin; Orhan, Fazıl; Cevit, Ömer; Tahan, Fulya; Kuyucu, Semanur; Bingöl, Ayşen Boz; Akçay, Ahmet; Yılmaz, Özge; Canıtez, Yakup; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.; 8988954700
Background: Childhood atopic dermatitis (AD) is classically accepted as initial finding of atopic march; however, non-atopic cases do not follow this course. The aim of this study was to determine the characteristics and prognosis of AD in childhood in Turkey. Methods: The study included 531 children with AD that presented to pediatric allergy departments in 11 different regions of Turkey. Age at diagnosis, total serum and inhalant-specific immunoglobulin E (IgE) levels and allergen skin prick test results were recorded retrospectively. Clinical characteristics like additional allergic diseases at presentation or during follow-up were recorded as well as duration of follow-up. Results: Mean age at diagnosis was 37.8 +/- 36.2 months. Mean IgE level was 318.3 +/- 677.8 IU/ml (median 100 IU/ml). Skin prick tests yielded positive results in 47% of children. At presentation, 31.6% of children reported additional allergic disease, while 11.7% developed allergic disease during follow-up. Among all, 46.6% had additional allergic disease at any point. IgE levels were significantly higher in children with additional allergic diseases (p = 0.001). Allergen skin prick test positivity and family history of allergic diseases increased the risk of additional allergic diseases significantly (OR = 3.90, 95% CI = 2.3-6.6 and OR = 1.89, 95% CI = 1.3-2.8, respectively). Conclusions: Allergic sensitization is not present in all cases of AD. Coexistence of additional allergic diseases is not as high as expected but more common in children who have been demonstrated to have atopic sensitization with high IgE levels and allergen skin prick test positivity.
The reliability and validity of the Turkish version of a childhood asthma control test
(Wiley, 2011-06) Soyer, Özge; Keskin, Özlem; Uzuner, Nevin; Yazicioglu, Mehtap; Kilic, Murat; Artac, Hasibe; Ozmen, Serap; Can, Demet; Zeyrek, D.; Çokuğraş, Haluk C.; Aydogan, Metin; Kuyucu, Semanur; INal, A.; Gurkan, Fuat; Orhan, Fazil; Yilmaz, Ozge; Boz, Bingol A.; Tahan, Fulya; Cevit, Ömer; Sekerel, B.; Sapan, Nihat; Uludağ Üniversitesi/Tıp Fakültesi/Pediatrik Alerji ve İmmünoloji Anabilim Dalı.
The reliability and validity of Turkish version of childhood asthma control test
(Springer, 2012-05) Şekerel, Bülent E.; Soyer, Özge Uysal; Keskin, Özlem; Uzuner, Nevin; Yazıcıoğlu, Mehtap; Kılıç, Mehmet; Artaç, Hasibe; Özmen, Serap; Can, Demet; Zeyrek, Dost; Çokuğraş, Halük; Aydoğan, Metin; Kuyucu, Semanur; İnal, Ayfer; Gürkan, Fuat; Orhan, Fazıl; Yılmaz, Özge; Boz, Ayşen Bingöl; Tahan, Fulya; Cevit, Ömer; Canıtez, Yakup; Uludağ Üniversitesi/Tıp Fakültesi.; 8988954700
Introduction: The reliability and validity of Turkish version of Childhood Asthma Control Test (C-ACT). Purpose: The management of asthma is an important as well as difficult issue of physician's daily practice particularly in busy clinical settings. C-ACT was created to identify asthma control levels in children aged 4-11 years. Our aim was to evaluate the reliability, validity and responsiveness of C-ACT in a Turkish sample of children with asthma. Method: In this multicenter study, 368 children were enrolled. C-ACT was completed every month by parents and patients who were evaluated in 3 visits within 2 month intervals. At each visit, physicians interpret the control level and decided for the treatment step as established in GINA guidelines. Results: The internal consistency reliability of the Turkish version of C-ACT (C-ACT1 to C-ACT5) was found to be 0.82, 0.83, 0.82, 0.82 and 0.80, respectively (reliability statistics, Cronbach's alpha). Test-retest reliability was 0.71. There was significant correlation between C-ACT and physician's assessment of asthma control at visit 1 (r = 0.65, P < 0.001). Conclusions: Turkish version of C-ACT is an accurate and reliable tool to evaluate asthma control in children aged 4-11 years. Its widespread use may facilitate appropriate assessment of asthma control and may lead to decrease the number of uncontrolled patients.
The utility of childhood asthma control test and its relationship with control measures and with the decisions made by asthma specialist
(Mosby-Elsevier, 2010-02) Şekerel, Bülent Enis; Keskin, Özlem; Uzuner, Nevin; Yazıcıoğlu, Mehtap; Kılıç, Murat; Artaç, Hasibe; Özmen, Serap; Can, Demet; Zeyrek, D.; Çokuğraş, Haluk; Soyer, Özge; Aydoğan, Metin; Kuyucu, Semanur; İnal, A.; Gürkan, Fuat; Orhan, Fazıl; Yılmaz, Özge; Bingöl, Ayşen; Tahan, Fulya; Cevit, Ömer; Sapan, Nihat; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.