Browsing by Author "YAZICI, ZEYNEP"

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Atipical teratoid rhabdoid tumor: Case report and review of the literature
(Kare Publ, 2014-01-01) Şahintürk, Kadriye; Özkan, Lütfi; Yazıcı, Zeynep; YAZICI, ZEYNEP; Tolunay, Şahsine; TOLUNAY, ŞAHSİNE; Taşkapılıoğlu, M. Özgür; Demirkaya, Metin; Demiröz Abakay, Candan; DEMİRÖZ ABAKAY, CANDAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Onkolojisi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nöroşurji Anabilim Dalı.; 0000-0001-5472-9065; AAW-5254-2020; AAI-2303-2021; ABB-8161-2020; AAI-1612-2021
Atipical teratoid rhabdoid tumor (ATRT) is a rare and highly agressive malign tumor in the early childhood. Mean survival has been reported as 6-11 months. Despite the optimal treatment is unclear surgery, chemotherapy and radiotherapy are the well known treatment options. We would like to report a 4 year old boy who had the diagnosis of ATRT at the temporooccipital region to make a contribution to the literature.
Clavicle duplication following physeal injury
(Springer France, 2019-04-01) Kandemirli, Sedat Giray; Kabar, Feyza; Kandemirli, Güzin Çakır; Gülleroğlu, Nadide Başak; Yazıcı, Zeynep; Kandemirli, Sedat Giray; KABAR, FEYZA; Kandemirli, Güzin Çakır; Gülleroğlu, Nadide Başak; YAZICI, ZEYNEP; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı.; AAI-2303-2021; A-1409-2017; FCU-5534-2022; CXO-0560-2022; EZQ-1350-2022
Clavicle duplication is a rare entity with limited number of cases reported. Congenital origin and trauma related mechanisms are the main hypotheses to explain this anatomical variation. In skeletally immature patient, trauma may cause physeal-metaphyseal injury in the distal clavicle rather than acromioclavicular strain. The distal epiphysis remains in continuity with acromion and has an intact periosteal sleeve. The periosteal sleeve is extremely osteogenic, and may lead to new bone formation between epiphysis and displaced metaphysis. This remodeling potential and the intact acromioclavicular joint allow the children to be followed by closed reduction. However, there can be new bone formation between epiphysis and displaced metaphysis, resulting in clavicle duplication. Herein, we present the radiographic and computed tomography findings of a post-traumatic duplication of the clavicle in a 5-year-old boy.
Clinical clues
(Aves Yayincilik, Ibrahim Kara, 2012-09-01) Gurpinar, Arif; GÜRPINAR, ARİF NURİ; Yazici, Zeynep; YAZICI, ZEYNEP; Celebi, Solmaz; ÇELEBİ, SOLMAZ; Hacimustafaoglu, Mustafa; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Cerrahi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0003-4646-660X; AAI-2303-2021
Diagnostic value of mediastinal lymphadenopathy in differentiating pulmonary tuberculosis from community-acquired pneumonia in children
(Briefland, 2022-08-01) Uçar, Ayşe Kalyoncu; Yeşil, Edanur; YAZICI, ZEYNEP; Yazıcı, Zeynep; ÇELEBİ, SOLMAZ; Hacımustafaoğlu, Mustafa; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; Ocakoğlu, Gökhan; OCAKOĞLU, GÖKHAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Bioistatistik Anabilim Dalı.; 0000-0003-4646-660X; 0000-0002-1114-6051; AAH-5180-2021
Background: Diagnosis of childhood pulmonary tuberculosis (TB) is often based on clinical features in combination with radiologic findings because of paucibacillary nature of the disease in children. It may be difficult to make a clinical diagnosis because of the overlapping clinical features of pulmonary TB and community-acquired pneumonia (CAP). On computed tomography (CT) scanning, the presence of typical LAP can suggest TB as a possible cause. Objectives: To compare the features of mediastinal LAPs between two patient groups based on contrast-enhanced chest CT. Methods: A total of 45 pulmonary patients with TB and 38 patients with CAP (aged <= 18 years) were enrolled in this retrospective study. The presence and CT features of lymph node involvement and the incidence of associating parenchymal/pleural findings were analyzed in two groups. Results: All patients with TB and 36 of the 38 patients with CAP had at least one mediastinal LAP. There was no significant difference between the two groups according to the incidence of lymph node and multiple site involvement and also involved lymph node stations (P > 0.05). However, lymph node size was larger in the TB group (P = 0.04). Twenty-two percent of patients with TB had mediastinal LAP without parenchymal/pleural involvement. Conclusions: Although the lymph node size was larger in TB group than in CAP group, CT features of mediastinal lymph node involvement overlapped between two groups. Nevertheless, mediastinal LAP without parenchymal/pleural involvement on CT is seen in a significant number of TB patients.
Differentiation of hepatocellular carcinoma from non-hepatocellular malignant tumours of liver by chemical-shift mri at 3 t
(W B Saunders Co Ltd, 2019-10-01) Savcı, Gürsel; SAVCI, GÜRSEL; Öztürk, Kerem; Özkaya, G.; ÖZKAYA, GÜVEN; Soylu, E.; Yazıcı, Zeynep; YAZICI, ZEYNEP; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; 0000-0001-9664-2347; 0000-0003-0297-846X; AAI-2303-2021; E-1228-2018; A-4421-2016; AAH-5481-2021
AIM: To evaluate the diagnostic performance of chemical shift magnetic resonance imaging (MRI) in distinguishing hepatocellular carcinomas (HCCs) from non-hepatocellular malignant tumours (non-HCCs) of the liver.MATERIALS AND METHODS: Patients with a diagnosis of malignant liver tumours examined at 3 T MRI were included in this retrospective study. Forty-seven HCCs and 75 non-HCCs that were studied with chemical-shift MRI between January 2012 and October 2016 were retrieved from the radiology database. Two blinded observers measured the signal intensities of the tumours, adjacent normal-looking liver parenchyma, and spleen on chemical-shift MRI. The fat quantification for HCCs, non-HCCs, and adjacent normal-looking liver parenchyma were calculated by using the spleen as a reference standard. The subtraction scores were calculated by subtracting fat percentages in liver parenchyma from those in tumours. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the fat percentage subtraction scores in distinguishing HCCs from non-HCCs were calculated.RESULTS: According to the optimal cut-off value acquired from both readers, a subtraction score >-0.26 was considered to be a HCC. Fat signal percentage subtraction scores were >=-0.26 in 45 of 47 HCCs and were <-0.26 in 69 of 75 non-HCCs. The sensitivity, specificity, PPV, and NPV of fat signal percentage subtraction score to differentiate HCCs from non-HCCs were found to be 95.7%, 89.3%, 84.9%, and 97.1%, respectively.CONCLUSION: Intracytoplasmic lipid in HCCs demonstrated by quantitative chemical-shift MRI may be a potentially powerful imaging biomarker to distinguish HCCs from the other malignant liver tumours.
Fibrous dysplasia: Clinicopathologic presentation of 36 cases
(De Gruyter Poland Sp Zoo, 2018-09-01) Özsen, Mine; ÖZŞEN, MİNE; Yalçınkaya, Ulviye; YALÇINKAYA, ÜLVİYE; Bilgen, Muhammed Sadık; Yazıcı, Zeynep; YAZICI, ZEYNEP; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Patoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi Anabilim Dalı.; 0000-0002-5771-7649; AAI-2303-2021; AAH-8924-2021; AAI-1609-2021
Objective: Fibrous dysplasia is a slowly progressing bone lesion resulting from displacement of the normal medullary bone with abnormal fibroosseous tissue. The aim of this study was to assess the similarities and differences of our cases in relation to published reports.Material and Method: In this study, the archives of the Uludag University Medical Faculty Department of Pathology were screened for fibrous dysplasia cases between 2004 and 2016.Results: Within the mentioned period, there were 36 cases diagnosed as fibrous dysplasia. There were 21 male, and 15 female cases with an average age of 27.8 +/- 14.8 years (range 7-79 years). The most frequently affected sites were femur, costae, and craniofacial bones. There was one case localized to metacarpal bone, a very rare affection site. There were 4 polyostotic cases including 2 cases of McCune-Albright syndrome. Pelvic bone was affected in the polyostotic type, similar to published reports. Unlike former reports, however, long tubular bones were affected in male patients in our series. In our series, 32 cases had classical fibrous dysplasia, 3 cases had fibrocartilaginous, and one case had fibroosseous variants. Four cases localized to costae were accompanied by aneurysmal bone cyst. The presenting symptom was pathological fractures in a total of 4 cases, 3 localized to the femur, and 1 to the costa. Recurrence occurred in 5 cases treated with curettage. Two of the monostotic fibrous dysplasia cases developed malignant transformation into osteosarcoma.Conclusion: We conclude that our series of fibrous dysplasia cases have slight differences and mainly similar characteristics with the series reported earlier, when all features are taken into consideration.
Horseshoe lung associated with scimitar syndrome
(Bmj Publishing Group, 2019-08-01) Gönen, Korcan Aysun; Canıtez, Yakup; CANITEZ, YAKUP; Bostan, Özlem Mehtap; BOSTAN, ÖZLEM MEHTAP; Yazıcı, Zeynep; YAZICI, ZEYNEP; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı.; 0000-0001-7707-2174; AAH-1789-2021
Horseshoe lung is a rare congenital anomaly and mostly accompanied by scimitar syndrome. Most aspects of this complex anomaly can be demonstrated via multidetector CT (MDCT). We present two baby girls who had horseshoe lung associated with right lung hypoplasia and scimitar vein. The chest roentgenograms showed displacement of the heart and mediastinum to the right with smaller right lung. Echocardiography revealed dextroposition, secundum atrial septal defect and bilateral slight peripheral pulmonary stenosis in the first case and dextroposition, severe pulmonary hypertension, secundum atrial septal defect and tricuspid regurgitation in the other one. On thoracic MDCT, the right lung and pulmonary artery were hypoplastic with cardiomediastinal shift to the right. There was an abnormal right pulmonary vein draining into the inferior vena cava on the lower zone of the right lung (scimitar vein). The posterobasal portions of the both lungs were fused through a midline isthmus behind the heart.
Intracranial calcification and hydrocephalus due to congenital toxoplasmosis
(Aves Yayıncılık, 2016-12-01) Hacımustafaoğlu, Mustafa; Çelebi, Solmaz; Orcan, Gökhan; Yazıcı, Zeynep; HACIMUSTAFAOĞLU, MUSTAFA KEMAL; ÇELEBİ, SOLMAZ; Orcan, Gökhan; YAZICI, ZEYNEP; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Enfeksiyon Hastalıkları Anabilim Dalı; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı, Çocuk Radyolojisi Bilim Dalı; 0000-0003-4646-660X; AAI-2303-2021; CTG-5805-2022; JHN-1091-2023; FSE-6855-2022
Malignant transformation of monostotic fibrous dysplasia into angiosarcoma in the proximal tibia
(Wolters Kluwer Medknow Publications, 2021-04-01) Yalçınkaya, Ulviye; YALÇINKAYA, ÜLVİYE; Narter, Selin; NARTER, SELİN; Bilgen, Muhammet S.; BİLGEN, MÜHAMMET SADIK; Yazıcı, Zeynep; YAZICI, ZEYNEP; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Genel Cerrahi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.
The majority of bone angiosarcomas are primary tumors while secondary angiosarcomas arise after radiation therapy or bone infarctus. This article presents a case of malignant transformation of monostotic fibrous dysplasia into angiosarcoma. An 80-year-old female presented with pain on right cruris. Radiological examination revealed a lesion with lytic areas and destruction of cortical bone on right tibia. Gross and histopathological examination showed two areas with an abrupt transition. The solid component was composed of curved, immature bony trabeculae in a fibroblastic stroma. The other component involved epitheloid cells forming slit-like vascular spaces. The diagnosis of angiosarcoma and fibrous dysplasia was given. Malignant transformation of fibrous dysplasia into angiosarcoma is extremely rare; as this is the sixth case in the existing literature. Prognosis of fibrous dysplasia is generally good and less than 1% of the patients develop a malignant tumor. Therefore, patients with fibrous dysplasia should be offered a life-long follow-up.
Normal or elevated prolactin is a good indicator to show pituitary stalk interruption syndrome in patients with multiple pituitary hormone deficiency
(Walter De Gruyter Gmbh, 2022-09-23) Eren, Erdal; Öngen, Yasemin Denkboy; Özgür, Taner; Özpar, Rıfat; Demirbaş, Özgecan; Yazıcı, Zeynep; Tarım, Ömer; EREN, ERDAL; DENKBOY ÖNGEN, YASEMİN; ÖZGÜR, TANER; ÖZPAR, RİFAT; DEMİRBAŞ, ÖZGECAN; YAZICI, ZEYNEP; TARIM, ÖMER FARUK; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Endokrinolojisi Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Radyolojisi Anabilim Dalı.; 0000-0002-1684-1053; 0000-0001-6649-9287; 0000-0002-6922-5203; 0000-0002-5322-5508; KHZ-1491-2024; JPK-3909-2023; AAH-5062-2021; AAI-2303-2021; FPE-9941-2022; GQX-9760-2022; CCU-8073-2022
Objectives To determine the importance of serum prolactin (PRL) in the detection of pituitary stalk interruption syndrome (PSIS) in children with multiple pituitary hormone deficiency (MPHD). We hypothesized that PRL elevation might be a diagnostic indicator of pituitary stalk pathologies. Methods Clinical, radiological, and laboratory features of the 50 cases of MPHD were studied. Results The median age at presentation of the 50 cases (52%, n=26 were female) was 6.61 (0.02-18.9) years. PSIS was detected in 60% (n=30), pituitary hypoplasia in 32% (n=16), partial empty sella in 6% (n=3), and only 2% (n=1) was reported as normal. Out of 50 patients, 21.3% (n=10) were hypoprolactinemic, 44.7% (n=19) were normoprolactinemic, and 34% (n=16) were hyperprolactinemic. The median PRL value was 27.85 (4.21-130) ng/mL in patients with PSIS and 5.57 (0-41.8) ng/mL in patients without PSIS. Additional hormone deficiencies, especially ACTH and LH were detected in follow-up. Conclusions Patients with normal or high prolactin levels deserve special attention regarding the possibility of PSIS. Furthermore, we emphasize the importance of regular follow-up and monitoring for multiple pituitary hormone deficiencies in all patients with a single pituitary hormone deficiency.
Pituitary stalk interruption syndrome (psis) is not a rare cause of the congenital hypopituitarism
(Karger, 2018-01-01) Eren, Erdal; Yazıcı, Zeynep; Demirbaş, Özgecan; Gülleroğlu, Nadide Başak; Tarım, Ömer; EREN, ERDAL; YAZICI, ZEYNEP; DEMİRBAŞ, ÖZGECAN; Gülleroğlu, Nadide Başak; TARIM, ÖMER FARUK; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Endokrinoloji Bölümü; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Radyoloji Bölümü; 0000-0002-1684-1053; 0000-0002-6922-5203; 0000-0002-5322-5508; AAI-2303-2021; JPK-3909-2023; GQX-9760-2022; EZQ-1350-2022; CCU-8073-2022
Prenatal diagnosis of fetal umbilical cord teratoma
(Walter De Gruyter Gmbh, 2014-08-01) Demir, Bilge Çetinkaya; Topal, Naile Bolca; Güneş, Esra Şahin; Yazıcı, Zeynep; Yalçınkaya, Ulviye; ÇETİNKAYA DEMİR, BİLGE; BOLCA TOPAL, NAİLE; Güneş, Esra Şahin; YAZICI, ZEYNEP; YALÇINKAYA, ÜLVİYE; Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0001-6845-9991; AAH-9834-2021; AAH-8924-2021; AAI-2327-2021; AAI-2303-2021; IDE-0603-2023
Umbilical cord teratomas are rare tumoral lesions of umbilical cord which have challenging antenatal diagnosis. The cord teratomas contain tissue from all three germ layers and have both cystic and solid components. This ultrasonographic appearance may help the clinician to clarify the correct diagnosis. We report a case of cord teratoma diagnosed prenatally by ultrasonography and magnetic resonance imaging. Since cord teratomas may lead to adverse fetal outcomes, close follow-up of the fetus is recommended.
Radiation exposure in the neonatal intensive care unit in newborns and staff
(Thieme Medical Publ Inc, 2021-07-28) Çakır, Salih Çağrı; Dorum, Bayram Ali; Köksal, Nilgün; Özkan, Hilal; Yazıcı, Zeynep; Parlak, Müfit; Gülleroğlu, Nadide Başak; ÇAKIR, SALİH ÇAĞRI; Dorum, Bayram Ali; Köksal, Nilgün; ÖZKAN, HİLAL; YAZICI, ZEYNEP; PARLAK, MÜFİT; Gülleroğlu, Nadide Başak; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Pediat Bölümü; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Bölümü; 0000-0001-5761-4757; 0000-0002-2823-8454; HJZ-4508-2023; AEZ-2469-2022; A-5375-2017; A-5375-2017; CZV-1969-2022; IGT-7005-2023; AAI-2303-2021; AAG-8521-2021; EZQ-1350-2022
Objective Portable X-rays remain one of the most frequently used diagnostic procedures in neonatal intensive care units (NICU). Premature infants are more sensitive to radiation-induced harmful effects. Dangers from diagnostic radiation can occur with stochastic effects. We aimed to determine the radiation exposure in premature infants and staff and determine the scattering during X-ray examinations in the NICU. Study Design In this prospective study, dosimeters were placed on premature infants who were <= 1,250 g at birth and <= 30 weeks of gestational age who stayed in the NICU for at least 4 weeks. The doses were measured at each X-ray examination during their stay. The measurements of the nurses and the doctors in the NICU were also performed with dosimeters over the 1-month period. Other dosimeters were placed in certain areas outside the incubator and the results were obtained after 1 month. Results The mean radiation exposure of the 10 premature infants, monitored with dosimeters, was 3.65 +/- 2.44 mGy. The mean skin dose of the six staff was 0.087 +/- 0.0998 mSV. The mean scattered dose was 67.9 +/- 26.5 mu Gy. Conclusion Relatively high exposures were observed in 90% of the patients and two staff. The radiation exposure levels of premature infants and staff may need to be monitored continuously.
Re: "Optic nerve cyst-like formation presenting as a delayed complication of optic nerve sheath fenestration"
(Lippincott Williams & Wilkins, 2015-03-01) Yazıcı, Bülent; Yazıcı, Zeynep; Yazıcı, Bülent; YAZICI, ZEYNEP; Bursa Uludağ Üniversitesi; 0000-0001-8889-1933; AAI-2303-2021; AAA-5384-2020
Robinow syndrome
(Galenos Yayıncılık, 2010-04-01) Gökalp, Gökhan; Eren, Erdal; Yazıcı, Zeynep; Sağlam, Halil; GÖKALP, GÖKHAN; EREN, ERDAL; YAZICI, ZEYNEP; SAĞLAM, HALİL; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0002-1684-1053; 0000-0002-6598-8262; C-7392-2019; AAI-2303-2021; AAI-2336-2021; JPK-3909-2023
Introduction: Robinow syndrome is characterized by dwarfism demonstrating short-limbed extremities, vertebral malsegmentation/malformation (hemivertebra), costal dysplasia, genital hypoplasia, and fetal facial appearance (wide and prominent forehead, hypertelorism, small and wide nose, molar hypoplasia, and retrognathia). It is a rare genetic disease which may present with either mild autosomal dominant form or severe recessive form. Vertebral and costal abnormalities are common diagnostic signs that may be severe. The disease presents with kyphoscoliosis and chest abnormalities along with thoracic vertebral fusion and hemivertebral appearance. Ribs may demonstrate fusion. Based on those involvements, the disease can be categorized as spondylothoracic, spondylocostal, ischiovertebral dysplasia, and cervicofaciothoracic syndrome. Diagnosis is established by the help of clinical characteristics. Radiography might contribute to the diagnosis by revealing changes in the skeletal system. Case Report: A three-year-old male patient presented with operated left undescendent testis and buried penis. On physical examination, he also had a dysmorphic face characterized by macrocephaly, hypertelorism, prominent eyes, a flattened nasal bridge, triangular-fish mouth, gingival hypertrophy and left hand clinodactyly. Radiographic examination documented mesomelic shortening of the radius-ulna, malsegmentation of the thoracal spine and the ribs fusion. Conclusion: Robinow syndrome is a rare syndrome which can be diagnosed by typical facial appearance and radiologic findings.
Role of cineangiography and renal ultrasonography in the diagnosis of urinary tract abnormalities associated with congenital heart disease
(Aves, 2009-12-01) Semizel, Evren; Yazıcı, Zeynep; YAZICI, ZEYNEP; Bostan, Özlem Mehtap; BOSTAN, ÖZLEM MEHTAP; Çil, Ergün; ÇİL, ERGÜN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0001-7707-2174; 0000-0003-3516-0082; AAI-2303-2021; AAH-3865-2021; AAG-8558-2021; AAG-9324-2021
Purpose: The incidence of urinary tract anomalies (UTA) associated with congenital heart disease (CHD) is high. The aim of this study is to investigate the role of cineurography and renal ultrasonography in the diagnosis of UTA associated CHD.Patients and Method: Cineurography of the 148 patients who underwent angiography, between January 2005 and July 2005, due to CHD were evaluated. Renal ultrasonographies were also performed to these patients. Intravenous pyelography was performed to the patients who were diagnosed as UTA by renal ultrasonography and/or cineurography.Results: Urinary tract anomalies were found in 23 of 148 patients by cineurography and in 22 of 148 patients by renal ultrasonography. Thirteen patients were diagnosed as UTA by both modalities. IVP was performed to 32 patients and UTA were detected in 24 of these 32 patients. 8 cincurograms yielded false-positive and 9 cincurograms yielded false-negative results. Ultrasonography produced 2 false negative results. Cineurography was able to show 62% of UTA accurately.Conclusion: Both cineurography and renal ultrasonography can be used to image the UTA associated CHD. The postangiocardiographic cineurogram appears to be a cost-effective, easy 188 and useful method of screening for silent UTA in children with CHD.
Secondary osteosarcomas diagnosed in a single institution: 7 cases in 10 years
(Carbone Editore, 2015-05-02) Yalçınkaya, Ulviye; Çetintaş, Sibel Kahraman; Bilgen, Muhammed Sadık; Yazıcı, Zeynep; Sevinir, Berrin Betül; Aydınlı, Ufuk; YALÇINKAYA, ÜLVİYE; Çetintaş, Sibel Kahraman; Bilgen, Muhammed Sadık; YAZICI, ZEYNEP; SEVİNİR, BETÜL BERRİN; Uludağ Üniversitesi/Tıp Fakültesi/Cerrahi Patoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Pediatrik Onkoloji Anabilim Dalı.; 0000-0002-3232-7652; AAH-1570-2021; AAI-2303-2021; AAA-7047-2020; AAH-8924-2021; ELH-9133-2022
Aims: Osteosarcoma is the most common, non-hematopoietic primary malignant tumor of bone. Osteosarcomas develop de novo in apparently normal bone. However, some benign bone tumors and non-neoplastic conditions may undergo malignant transformation into osteosarcomas. Such osteosarcomas are called secondary osteosarcoma. The scope of this article is to report on a ten-year experience of secondary osteosarcoma in a single institution.Materials and methods: The archives of Uludag University Medical School Department of Pathology were screened for cases of secondary osteosarcoma between January 2002 and June 2013. Demographics, clinical and pathological data are listed.Results: Of the 62 cases of osteosarcoma diagnosed in the period, 7 were secondary osteosarcomas. There were 5 male and 2 female patients. In 4 cases, the secondary osteosarcomas were due to radiation therapy. The index lesion was Paget's disease of bone, bone infarct and giant cell tumor of bone in the other cases. Index lesions included breast carcinoma, Ewing's sarcoma, rhabdomyosarcoma, and primitive neuroectodermal tumor for postradiation osteosarcomas. Unfortunately all patients passed away except for 3 cases of postradiation osteosarcoma.Conclusion: In cases of benign situations having a tendency of malignant transformation including giant cell tumor of bone, bone infarct, Paget's disease, and areas of former radiation therapy, clinical and radiological findings may be of great help in detecting in earlier stages of malignant transformation, and more promising for a disease free survival.
Spondylocostal dysostosis associated with diaphragmatic hernia and neural tube defects
(Lippincott Williams & Wilkins, 2008-04-01) Çetinkaya, Merih; Özkan, Hilal; Köksal, Nilgün; Yazıcı, Zeynep; Yalçınkaya, Ulviye; Çetinkaya, Merih; ÖZKAN, HİLAL; Köksal, Nilgün; YAZICI, ZEYNEP; YALÇINKAYA, ÜLVİYE; Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı/Neonatoloji Bilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; AFP-9671-2022; JLK-4920-2023; AAI-2303-2021; AAH-8924-2021; FFA-6764-2022
Superb microvascular imaging in assessment of synovitis and tenosynovitis in juvenile idiopathic arthritis
(Lippincott Williams & Wilkins, 2021-03-01) Kandemirli, Sedat Giray; Çicek, Fatih; Erdemli Gürsel, Başak; Bilgin, Cem; Kiliç, Sara Sebnem; Yazıcı, Zeynep; Çicek, Fatih; ÇİÇEK, FATİH; Erdemli Gürsel, Başak; ERDEMLİ GÜRSEL, BAŞAK; Bilgin, Cem; BİLGİN, CEM; Kiliç, Sara Sebnem; KILIÇ GÜLTEKİN, SARA ŞEBNEM; Yazıcı, Zeynep; YAZICI, ZEYNEP; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; 0000-0001-7348-7081; 0000-0001-8571-2581; AAH-1658-2021; HHS-7433-2022; JKI-5906-2023; AAH-6568-2021
The aim of this study is to evaluate the diagnostic utility of superb microvascular imaging (SMI) in assessment of synovitis/tenosynovitis in juvenile idiopathic arthritis in comparison to power Doppler ultrasound. Thirty juvenile idiopathic arthritis cases with active clinical findings and ultrasound features of effusion and/or tenosynovitis were further imaged with power Doppler and SMI. For classification of synovial inflammation, a semiquantitative scale (4 points) adopted by Outcome Measures in Rheumatology was used.A total of 35 knee, 2 hip, 2 ankle, 2 wrist, 2 elbow joints, and 6 flexor hallucis longus/tibialis posterior tenosynovitis were assessed. In knee joint, power Doppler and SMI scales were the same for 23 (65.7%) joints, SMI upgraded scale from 0 to 2 in single joint (2.9%); 1 to 2 (14.3%) in 5 joints; and 2 to 3 (17.1%) in 6 joints. For other joints, power Doppler and SMI scales were the same for 5 (62.5%) joints. Superb microvascular imaging upgraded scale from 1 to 2 (25%) in 2 joints and 1 to 3 (12.5%) in a single joint. For flexor hallucis longus/tibialis posterior tenosynovitis, power Doppler and SMI scales were the same for two cases (33.3%). Superb microvascular imaging upgraded scale from 0 to 2 in two cases (33.3%); and 2 to 3 (33.3%) in 2 cases. There was no case of SMI scale downgraded compared with power Doppler scale.Superb microvascular imaging is a feasible technique in the assessment of synovial inflammation and tenosynovitis in juvenile idiopathic arthritis. Superb microvascular imaging has higher sensitivity compared with power Doppler ultrasound in depiction of increased vascularity.
Two cases diagnosed with tuberosclerosis in neonatal period
(Galenos Yayıncılık, 2014-12-01) Varal, İpek Güney; Köksal, Nilgün; Özkan, Hilal; Bostan, Özlem; Bağcı, Onur; Uysal, Fahrettin; Yazıcı, Zeynep; Doğan, Pelin; Varal, İpek Güney; Köksal, Nilgün; BOSTAN, ÖZLEM MEHTAP; ÖZKAN, HİLAL; Bağcı, Onur; UYSAL, FAHRETTİN; YAZICI, ZEYNEP; Doğan, Pelin; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı/Neonatoloji Bilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı/Pediatrik Kardiyoloji Bilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı/Pediatrik Radyoloji Bilim Dalı.; 0000-0001-7707-2174; 0000-0001-9308-9806; CIR-8129-2022; JGS-7600-2023; JJY-3921-2023; AAG-8558-2021; KYP-5736-2024; AAH-4421-2021; AAI-2303-2021; CNZ-3688-2022
Congenital heart tumors are very rare and the most common type is the rhabdomyoma. Frequency during autopsy is between 0.027-0.08%. Moreover 51-86% of these tumors are associated with tuberosclerosis. Also hamartomas might accompany, particularly on the central nervous system and skin, kidney, liver, lung and heart. In this paper, two cases diagnosed with tuberculosis who showed rhabdomyomas in fetal echocardiography in the antenatal period and were seen to have tubers in cranial magnetic resonance (MR) postnatally, are presented.