2001 Cilt 20 Sayı 3

Permanent URI for this collectionhttps://hdl.handle.net/11452/12866

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    Comparison of the effects of classical fluid therapy and total parenteral nutrıtion in the treatment of dogs with gastroenteritis
    (Uludağ Üniversitesi, 2001-09-27) Yılmaz, Zeki; Şentürk, Sezgin; Gölcü, Esin; Yalçın, Ebru; İlçöl, Yeşim; Torun, Serhat; Temizel, Mutlu; Veteriner Fakültesi
    In the study, it was aimed to compare the effect of clasical fluid therapy and total parenteral nutrition (TPN) in the management of dogs with gastroenteritis. Seventeen dogs with gastroenteritis were divided into 2 groups at the treatment stage: TPN group (n=10) and control group (n=7). Solution of TPN group included an aminoacids solution (8.5% Fre-Amine), a lipid solution (20% lipovenouse), a dextrose solution (20% Dextrose), a balanced electrolyte solution (Lactated Ringers) and a vitamin solution (Polybion). The combination of lactated ringers and dextrose (5%) solutions were administered to dogs in control group. Solutions were administered for 2 days in each group. Clinical and laboratory examination were carried out, before and at 24th, 48thand 72nd hr after initiation of the treatment. Body temperature was gradually decreased in the control and TPN groups. The alterations of heart and respiratory rates were similar in each group. Capillary filling time was gradually decreased and within normal limits at 72nd hr in both group (p<0.05). Hematologic parameters, except from PLT count, were higher at baseline in the TPN group than in the control group. While total protein and albumin concentrations were decreased from baseline to the 48th hr, they increased at 72nd hr in the control group. Urea and Cr values were decreased after the treatment in both groups. Cholestrerol and TG concentrations were decreased at 72nd hr after the discontinued infusion in the TPN group. While alanine transaminase enzyme activity was increased from base line to at 48th hr, it decreased at 72nd hr in the TPN group. Glucose concentration at 24th hr in the control group was significantly lower than in the TPN group (p<0.05). Plasma osmolality was lower in the TPN group througout the study (p<0.01). Sodium and chloride concentrations in the TPN group were lower than the control group at 24 hr (p<0.05). Potassium concentrations in serum samples of the TPN applied group were lower through the study than those of control group (p<0.05). As a result, it was concluded that the total parenteral nutrition could be used effectively and safety for 2 days in the management of dogs with gastroenteritis