Browsing by Author "Ege, Ercüment"

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A fatal complication of dermatomyositis: Spontaneous pneumomediastinum
(Kare Yayınevi, 2016-04-01) Çetinoğlu, Ezgi Demirdoğen; Dalkılıç, Ediz; Erol, Muharrem; Acet, Nilüfer Aylin; Ursavaş, Ahmet; Ege, Ercüment; Çetinoğlu, Ezgi Demirdoğen; DALKILIÇ, HÜSEYİN EDİZ; Erol, Muharrem; ACET ÖZTÜRK, NİLÜFER AYLİN; URSAVAŞ, AHMET; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Romatoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; 0000-0002-7400-9089; 0000-0002-6375-1472; AAH-9812-2021; JHC-5173-2023; JEN-3243-2023; Z-1424-2019; AAI-3169-2021; CPF-5844-2022
Interstitial lung disease (ILD) is a negative prognostic factor associated with increased morbidity and mortality in patients with dermatomyositis (DM). Spontaneous pneumomediastinum is a rare complication of DM and it can be fatal. We present a 48-year-old woman with DM and ILD complicated by pneumomediastinum without pneumothorax and subcutaneous emphysema.
An analysis of patients diagnosed with pulmonary embolism in terms of clinical and meteorological data
(Saudi Medical Journal, 2006) Ercan, İlker; Coşkun, Funda; Cangür, Şengül; Ursavaş, Ahmet; Uzaslan, Esra; Ege, Ercüment; Kan, İ.; Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları ve Tüberküloz Anabilim Dalı.; 0000-0003-3604-8826; 0000-0002-2382-290X; AAD-1271-2019; AAI-3169-2021; 6603789069; 21734137500; 8604063700; 8329319900; 8761653500; 6701341320; 15032979000
Association between self reported snoring, STOP questionnaire and postoperative pulmonary complications in patients submitted to ortophaedic surgery
(Pagepress Publication, 2013-01-18) Ursavaş, Ahmet; Güven, Tahir; Coşkun, Funda; Ege, Ercüment; Yılmazlar, Aysun; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji Anabilim Dalı.; 0000-0003-3604-8826; AAD-1271-2019; AAI-3169-2021; 8329319900; 46761035100; 21734137500; 6701341320; 55899579900
Background: Obstructive sleep apnea (OSA) may increase perioperative complications. The aim of this study was to determine the relationship among postoperative pulmonary complication, snoring and STOP questionnaire in patients with ortophaedic surgery. Methods: 1,406 consecutive records of patients who had undergone elective ortophaedic surgery during the period January 2005-December 2008 were investigated retrospectively. Demographic information, sleep symptoms, STOP questionnaire, comorbidities and outcome data were collected. Results: There were 289 (20.5%) snorers and 1,117 (79.5%) non-snorers in the study group. There was no significant difference between snorer and non-snorer patients (p > 0.05) in the prevalence of pneumonia and respiratory failure. But in snorer patients the rate of postoperative atelectasis was significantly higher than in non-snorer group (p < 0.0001). The STOP Questionnaire was given to 1,406 patients and 147 (10.4%) out of them were classified at high risk of OSA. There was no significant difference in the prevalence of pneumonia and respiratory failure between low and high risk group (p > 0.05). However, in high risk patients the occurrence of postoperative atelectasis was significantly higher than in low risk group (p < 0.0001). Conclusion: Postoperative atelectasis was significantly more prevalent in the high risk group according to STOP questionnaire.
Association between serum neopterin, obesity and daytime sleepiness in patients with obstructive sleep apnea
(W B Saunders, 2008-08) Ursavaş, Ahmet; Karadağ, Mehmet; Oral, Arzu Yılmaztepe; Demirdöǧen, Ezgi Şen; Oral, Haluk Barbaros; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji ve Enfeksiyon Hastalıkları Anabilim Dalı.; 0000-0003-0463-6818; 0000-0003-0463-6818; 0000-0002-7400-9089; 0000-0002-7400-9089; AAI-3169-2021; A-5841-2017; AAG-8744-2021; AAH-9812-2021; K-7285-2012; 8329319900; 6601970351; 23091316500; 14062849300; 7004498001; 6701341320
Objective: Obesity and obstructive sleep apnea (OSA) and systemic inflammation may interact through biochemical pathways. Neopterin (NP) is a monocyte/macrophage activation marker produced by macrophages in response to interferon-gamma secreted by activated T lymphocytes. This study examines the association between NP, obesity and OSA. Patients and methods: The study included 22 newly diagnosed OSA (+) patients and 18 OSA patients. Subjects with history of coronary artery disease, transplant patients, history of alcohol and drug abuse, history of HIV and any other significant medical. illnesses such as active infections, autoimmune disease, malignancy, liver disease, pulmonary disease (COPD, asthma, ...), neuromuscular disease, patients on immunomodulating therapy or HMG-CoA reductase inhibitors were excluded. Results: There were no significant differences in age, body mass index (BMI), and smoking habits of the OSA (+) patients and OSA (-) patients. Serum NP levels did not show any significant difference between the OSA (+) patients and OSA (-) patients, however, NP levels were positively correlated with BMI (r = 0.320, p = 0.044). There was no significant correlation between NP and any of the polysomnographic parameters. The result of stepwise regression analyses (r 2 = 0.320, p < 0.001) showed that high serum NP levels (p = 0.004) and apnea-hypopnea index (AHI) were a risk factor for elevated Epworth sleepiness score, independent of BMI. Conclusion: We suggest that serum NP levels correlate with BMI. There was a significant relationship between serum NP levels and excessive daytime sleepiness in OSA patients.
Behçet hastalığında bilateral pulmoner arter anevrizması ve tromboembolizmi
(Uludağ Üniversitesi, 1990) Durmayaz, Muammer; Özyardımcı, Nihat; Gözü, R. Oktay; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.
Kliniğimize hemoptiziyle başvuran, bilateral pulmoner arter anevrizması ve akciğer tromboembolizmi tanısı konan 28 yaşında bir Behçet hastalığı olgusu sunulmuş, ilgili literatür gözden geçirilmiştir. Anevrizma radyolojik olarak bilgisayarlı tomografi ile ortaya konmuştur.
Bronkiolo-alveoler karsinoma (Bir olgu nedeniyle)
(Uludağ Üniversitesi, 1990) Akkaya, Ahmet; Özyardımcı, Nihat; Gözü, Oktay; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.
Bronkiolo-alveoler karsinoma akciğerin periferik tip tümörlerindendir. Klinik gidişiyle ve radyolojik bulgularıyla oldukça ilginç özellikleri olan bir bronkiolo-alveoler karsinoma olgusu takdim edilmiştir.
Bronş kanserli olgularda akciğer perfüzyon sintigrafisi bulguları
(Uludağ Üniversitesi, 1988) Yüksel, Eser Gürdal; Özyardımcı, Nihat; Gözü, Oktay; Ege, Ercüment; Yalın, Ahmet; Aksel, Nilüfer Çakanlar; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.
Bu çalışmada 1986 yılı içinde kliniğimize müracaat etmiş, "Bronş Ca" tanısı konmuş ve tanı bronkoskopik ve patolojik olarak teyid edilmiş, 7 erkek hastada akciğer perfüzyon sintigrafisi bulguları incelenerek akciğerlerdeki perfüzyon bozukluğu ile kanser dokusunun yerleşim yeri arasındaki uygunluk tartışıldı.
Catheter-directed therapy in acute pulmonary embolism with right ventricular dysfunction: A promising modality to provide early hemodynamic recovery
(Int Scientific Information, 2016-04-15) Dilektaşlı, Aslı Görek; Çetinoğlu, Ezgi Demirdoğen; Acet, Nilüfer Aylin; Erdoğan, Cüneyt; Ursavaş, Ahmet; Özkaya, Güven; Coşkun, Funda; Karadağ, Mehmet; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; 0000-0002-9027-1132; 0000-0002-6375-1472; 0000-0003-3604-8826; 0000-0003-0297-846X; AAG-8744-2021; Z-1424-2019; AAD-1271-2019; A-4421-2016; AAI-3169-2021; 36466376600; 57189524206; 56507253300; 8293835700; 8329319900; 16316866500; 21734137500; 6601970351; 6701341320
Background: Catheter-directed therapy (CDT) for pulmonary embolism (PE) is considered as an alternative to systemic thrombolysis (ST) in patients with hemodynamically unstable acute PE who are considered at high bleeding risk for ST. We aimed to evaluate the efficacy and safety of CDT in the management of acute PE with right ventricular dysfunction (RVD). The primary outcomes were mortality, clinical success, and complications. Secondary outcomes were change in hemodynamic parameters in the first 24 hours following the procedure. Material/Methods: Medical records of consecutive patients diagnosed as having acute massive or submassive PE with accompanying RVD treated by immediate CDT at our institution from January 2007 to January 2014 were reviewed. Patient characteristics, mortality, achievement of clinical success, and minor and major bleeding complications were analyzed in the overall study group, as well as massive vs. submassive PE subgroups. Change in hemodynamic parameters in the second, eighth, and 24th hours after the CDT procedure were also analyzed. Results: The study included 15 consecutive patients (M/F=10/5) with a mean age of 54.2 +/- 16.6 years who underwent immediate CDT. Nine of the patients had submassive PE, and 6 had massive PE. In-hospital mortality rate was 13.3% (95% CI, 0.04-0.38). One major, but not life-threatening, bleeding episode was evident in the whole group. Hemodynamic parameters were stabilized and clinical success was achieved in 14/15 (93.3%; 95% CI, 70.2-98.8) of the patients in the first 24 hours. Notably, the hemodynamic recovery was significantly evident in the first 8 hours after the procedure. Conclusions: CDT is a promising treatment option for patients with acute PE with RVD with no fatal bleeding complication. In experienced centers, CDT should be considered as a first-line treatment for patients with acute PE and RVD and contraindications for ST, with the advantage of providing early hemodynamic recovery.
Clinical effectiveness of nebulised budesonide in the treatment of acute asthma attacks
(Turkish Assoc Tuberculosis & Thorax, 2006-01-01) Ediger, Dane; COŞKUN, NECMİYE FUNDA; EDİGER, DANE; Coskun, Funda; Kunt Uzaslan, Esra; Gürdal Yüksel, Eser; Ege, Ercüment; Gözü, Oktay; Karadag, Mehmet; KARADAĞ, MEHMET; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; 0000-0002-2954-4293; 0000-0003-3604-8826; 0000-0002-9027-1132; AAG-8744-2021; AAD-1271-2019; AAE-9142-2019
Nebulized budesonide (NB) might offer topical anti-inflammatory activity and be an alternative to systemic corticosteroid (SC) in the treatment of acute asthma. The aim of this study was to compare the effect of NB with SC on lung function and clinical findings of adult patients with acute asthma. Thirty patients admitted to clinic with asthma attack (F/M:26/4; mean age: 47.1 +/- 2.1 years) were enrolled to the study. The patients were randomized into three groups; Group I were treated with NB alone (4 mg/day), Group II SC alone (1 mg/kg/day methylprednisolone), Group III NB plus SC. Pulmonary functions and respiratory symptom scores were measured and recorded before and during 7 days of study. Spirometric parameters significantly improved in all groups at 7th day significantly (p< 0.05) without a difference among groups (p> 0.05). FEV 1 % levels increased significantly at the first day of study in Group I and III (p< 0.05), but didn't change in Group II until 5th day of study. The mean symptom scores decreased significantly at the second day in Group I (p< 0.05), and at the 4th day in other groups. NB with or without SC improved successfully airway obstruction and symptoms in patients hospitalized with acute asthma attack as the 1st treatment day in comparison with SC alone and this effect lasted for 7 days. Regarding the superior safety profile and comparable efficacy with SC, NB might be an alternative to the patients with moderate-severe asthma attacks.
Clinical, functional characteristics and exercise capacity of the frequent exacerbator copd phenotype
(Amer Thoracic Soc, 2015-01-01) Uzaslan, Esra; Dilektaşlı, Aslı Görek; Çetinoğlu, Ezgi Demirdogen; Budak, Ferah; Coşkun, Funda; Ursavas, Ahmet; Ege, Ercüment; UZASLAN, AYŞE ESRA; GÖREK DİLEKTAŞLI, ASLI; Çetinoğlu, Ezgi Demirdogen; BUDAK, FERAH; COŞKUN, NECMİYE FUNDA; URSAVAŞ, AHMET; Ege, Ercüment; Uludağ Üniversitesi; 0000-0001-7099-9647; 0000-0002-7400-9089; 0000-0001-7625-9148; 0000-0003-3604-8826; JPK-7012-2023; F-4657-2014; AAD-1271-2019; AAI-3169-2021; IZP-9398-2023; CDI-1977-2022; DTT-7416-2022; AAH-9812-2021
Coexistence of sarcoidosis and sjogren's syndrome: A case-report
(Amer, 2015-10-01) Dilektaşlı, Aslı Görek; Çetinoğlu, Ezgi Demirdoğen; Durmuş, Eda; Uzaslan, Esra; Ege, Ercüment; Karadağ, Mehmet; GÖREK DİLEKTAŞLI, ASLI; Çetinoğlu, Ezgi Demirdoğen; Durmuş, Eda; UZASLAN, AYŞE ESRA; Ege, Ercüment; KARADAĞ, MEHMET; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı; 0000-0001-7099-9647; 0000-0002-7400-9089; 0000-0002-9027-1132; AAG-8744-2021; JPK-7012-2023; DTT-7416-2022; ETU-0442-2022; CDI-1977-2022; CPF-5844-2022
Comorbidies in patients hospitalized for acute exacerbation of copd
(Wiley, 2013-11-01) Dilektaşlı, Aslı Görek; Çetinoğlu, Ezgi Demirdoğen; Coşkun, Funda; Özkaya, Güven; Ege, Ercüment; Uzaslan, Esra; GÖREK DİLEKTAŞLI, ASLI; Çetinoğlu, Ezgi Demirdoğen; COŞKUN, NECMİYE FUNDA; ÖZKAYA, GÜVEN; Ege, Ercüment; UZASLAN, AYŞE ESRA; Uludağ Üniversitesi/Tıp Fakültesi/Biyostat Bölümü; Uludağ Üniversitesi/Tıp Fakültesi/Diş Bölümü; 0000-0001-7099-9647; 0000-0002-7400-9089; 0000-0003-3604-8826; 0000-0003-0297-846X; AAD-1271-2019; JPK-7012-2023; A-4421-2016; DTT-7416-2022; AAH-9812-2021; CPF-5844-2022; CDI-1977-2022
Does body mass index of patients effects severity of disease in hospitalized asthmatics?
(Elsevier, 2005-10) Uzaslan, Esra; Gözü, Oktay; Coşkun, Funda; Ediger, Dane; Karadağ, Mehmet; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/İmmünoloji ve Alerjik Hastalıklar Anabilim Dalı.; 0000-0002-9027-1132; 0000-0003-3604-8826; AAE-9142-2019; AAG-8744-2021; AAD-1271-2019
In this study, we aimed to analyze the effects of obesity to the severity of the disease, by investigating the correlation between body mass index (BMI) and characteristics of asthma in hospitalized asthma patients. Characteristics of asthma related factors and BMI of patients analyzed retrospectively from the data obtained from the clinic files of 160 hospitalized patients (41male,119female, mean age 46.5±1.1years)who were followed in our department.Body mass index was calculated as body weight/height (kg/m2).Patients were divided and evaluated in three groups according to their BMI; Group1: BMI<22.5 thin, Group2: 22.5≤ BMI<30 normal or overweight,Group3: BMI≥30 obese.The mean BMI of the whole patients was 28.3±0.5, whilst the mean BMI of patients in Group 1 was 32.9±2.9,in Group 2 was 46.6 ± 1.6,and in Group 3 was 49.2 ± 1.5. The 20% of patients in Group 1, 47% of patients in Group2 and 33% of patients in Group3 were atopic The 33%of the asthmatic patients was also diagnosed to have allergic rhinites.The 8.4% of patients (n:13)had a history of childhood asthma (54% in Group1, 31% in Group2 and 15% in Group3).The percentage of patients with the history of childhood asthma was significantly higher in Group1 than in Group2 and Group 3.Although there was not any significant difference in the mean eosinophiles counts and mean serum ECP levels of patients, those values were lower in Group3 than in other groups.There was not any significant difference in mean outdoor and indoor allergen sensitivity scores of patients among groups. Mean medication score (number of controller drugs) of patients in Group1 was significantly lower than in Group2 and Group3.The lung function parameters of FEV1 and PEF were not significantly different among groups, but predicted value of FVC was significantly higher in Group1 than Group2 and Group3 According these results we came to the conclusion that obesity was a severity factor in hospitalized asthmatic patients. Asthma outcomes was effected badly with increasing body weight in asthmatics.
Erişkinde konjenital posterolateral diyafragma hernisi (bir olgu nedeniyle)
(Uludağ Üniversitesi, 1990) Durmayaz, Muammer; Özyardımcı, Nihat; Gözü, R. Oktay; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.
Konjenital posterolateral diafragma hernisi (Bochdalek) çocuklarda sıktır, ancak erişkinlerde nadir görülür. 23 yaşında bir erişkinde geç olarak ortaya çıkan konjenital diyafragma hemi olgusu ilginç bulunduğu için sunulmuştur.
Evaluation of fibrinogen levels in patients with obstructive sleep apnea syndrome
(Wiley, 2013-11-01) Çetinoğlu, Ezgi Demirdoğen; Ursavaş, Ahmet; Karadağ, Mehmet; Coşkun, Funda; Ediger, Dane; Uzaslan, Esra; Ege, Ercüment; Gözü, Oktay; Çetinoğlu, Ezgi Demirdoğen; URSAVAŞ, AHMET; KARADAĞ, MEHMET; COŞKUN, NECMİYE FUNDA; EDİGER, DANE; UZASLAN, AYŞE ESRA; Ege, Ercüment; Gözü, Oktay; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; 0000-0002-7400-9089; 0000-0002-9027-1132; 0000-0003-3604-8826; 0000-0002-2954-4293; AAI-3169-2021; AAD-1271-2019; AAG-8744-2021; JPK-7012-2023; AAE-9142-2019; AAH-9812-2021; CDI-1977-2022; CPF-5844-2022; JLC-5863-2023
Evaluation of post-treatment effects of leukotriene receptor antagonists
(Elsevier, 2005-10) Uzaslan, Esra; Coşkun, Funda; Ediger, Dane; Rodoplu, Erkan; Karadağ, Mehmet; Ege, Ercüment; Gözü, Oktay; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; 0000-0002-9027-1132; 0000-0003-3604-8826; AAG-8744-2021; AAD-1271-2019
Evaluation of thyroid hormone levels and somatomedin-C (IGF-1) in patients with chronic obstructive pulmonary disease (COPD) and relation with the severity of the disease
(Turkish Assoc Tuberculosis & Thorax, 2009-01-01) Coşkun, Funda; Ege, Ercüment; Uzaslan, Esra; Ediger, Dane; Karadağ, Mehmet; Gözü, Oktay; COŞKUN, NECMİYE FUNDA; Ege, Ercüment; UZASLAN, AYŞE ESRA; EDİGER, DANE; KARADAĞ, MEHMET; Gözü, Oktay; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; 0000-0003-3604-8826; 0000-0002-2954-4293; 0000-0002-9027-1132; AAD-1271-2019; CPF-5844-2022; AAI-1004-2021; AAE-9142-2019; AAG-8744-2021; EWV-3115-2022
Chronic obstructive pulmonary disease (COPD) has recently become a significant cause of mortality and morbidity. In the present study, we aimed to investigate the relationship between the severity of the disease and levels of serum thyroid hormones and somatomedin-C [Insulin-Like Growth Factor (IGF-1)]. Sixty one COPD cases (group 1) were enrolled. Control group (group 2) consisted of 20 healthy individuals. Blood samples were obtained for the analysis of arterial blood gases and hormone levels and respiratory function tests were performed on the same day. Measured hormone levels were compared between group 1 and group 2. Among thyroid hormone levels, there was no significant difference in thyroid stimulating hormone and free T3 between group 1 and 2 whereas free T4 levels were significantly higher in group 1 (p< 0.01). Additionally, mean IGF-1 levels were significantly lower in group 1 (p< 0.005). When three groups, classified according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria, were compared, significant differences were observed between mild-moderate COPD cases and severe patients with respect to free T3 and IGF-1 levels (p< 0.05). Hormone levels in COPD patients change depending on the severity of the disease. In the future hormone therapies can use for the COPD treatments. Further studies with larger sample sizes are required to confirm our conclusions.
Factors affecting in-hospital mortality in patients with chronic obstructive pulmonary disease exacerbation
(European Respiratory Soc Journals, 2013-09-01) Dilektaşlı, Aslı Görek; Uzaslan, Esra; Çetinoğlu, Ezgi Demirdöğen; Acet, Nilüfer Aylin; Ediger, Dane; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; 0000-0002-6375-1472; AAI-1004-2021; AAE-9142-2019; Z-1424-2019
Gender differences in hospitalized patients with acute exacerbation of COPD
(European Respiratory Soc Journals, 2013-09-01) Uzaslan, Esra; Çetindoğan, Ezgi; Dilektaşlı, Aslı Görek; Coşkun, Funda; Ediger, Dane; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; 0000-0003-3604-8826; AAE-9142-2019; AAD-1271-2019; AAI-1004-2021
Ghrelin, leptin, adiponectin, and resistin levels in sleep apnea syndrome: Role of obesity
(Wolters Kluwer, 2010-07) Ursavaş, Ahmet; İlçöl, Yeşim Özarda; Nalcı, Nazan; Karadağ, Mehmet; Ege, Ercüment; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.; 0000-0002-9027-1132; AAL-8873-2021; AAG-8744-2021; AAI-3169-2021; 8329319900; 35741320500; 24448320900; 6601970351; 6701341320
Aim: The aim of this study was to investigate the relationship among plasma leptin, ghrelin, adiponectin, resistin levels, and obstructive sleep apnea syndrome (OSAS). Methods: Fifty-five consecutive newly diagnosed OSAS patients and 15 age-matched nonapneic controls were enrolled in this study. After sleep study between 8:00 AM and 9:00 AM on the morning, venous blood was obtained in the fasting state to measure ghrelin and adipokines. Results: Serum ghrelin levels of OSAS group were significantly (P < 0.05) higher than those of the control group. No significant difference was noted in the levels of leptin, adiponectin, and resistin in OSAS group when compared to controls. There was a significant positive correlation between ghrelin and apnea-hypopnea index (AHI) (r = 0.237, P < 0.05) or the Epworth sleepiness scale (ESS) (r = 0.28, P < 0.05). There was also a significant positive correlation between leptin and body mass index (r = 0.592, P < 0.0001). No significant correlation was observed between leptin, adiponectin, resistin, and any polysomnographic parameters. Conclusion : Our findings demonstrated that serum ghrelin levels were higher in OSAS patients than those of control group and correlated with AHI and ESS. Further studies are needed to clarify the complex relation among OSAS, obesity, adipokines, and ghrelin.