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YILMAZ, MEHMET UĞUR

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YILMAZ

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MEHMET UĞUR

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    Publication
    Laparoscopy is a definitive diagnostic method for auto-amputated ovary in infants
    (Springer, 2022-08-14) Parlak, Ayşe; Çelik, Fatih; Sezer, Bilge Türedi; Yılmaz, Mehmet Uğur; Kılıç, Nizamettin; Kiriştioğlu, İrfan; Balkan, Emin; Doğruyol, Hasan; PARLAK, AYŞE; ÇELİK, FATİH; TÜREDİ SEZER, BİLGE; YILMAZ, MEHMET UĞUR; KILIÇ, NİZAMETTİN; KIRIŞTIOĞLU, İRFAN; BALKAN, MEHMET EMİN; Doğruyol, Hasan; Tıp Fakültesi; Çocuk Cerrahisi Ana Bilim Dalı; Çocuk Ürolojisi Bilim Dalı; 0000-0001-7686-2561; 0000-0003-2728-9521; 0000-0003-3532-0912; 0000-0002-5662-9479; AAI-4220-2021; AAD-3537-2020; AAH-6766-2021; AAI-2145-2021; JYY-5340-2024; GRA-7433-2022; FDI-4997-2022; ETC-9949-2022
    Purpose Antenatal auto-amputation of the ovary is an extremely rare event, and its diagnosis is difficult. We aimed to retrospectively review the cases with antenatal auto-amputation, where the diagnosis was made based on detection of free-floating cyst during surgery. Methods Patients diagnosed with auto-amputated ovary during the surgery between 2012 and 2021 were included in the study. The data were reviewed retrospectively. Clinical, radiological, surgical, and histopathological findings were recorded. Results Eight patients underwent surgery for an abdominal cystic mass. The age range of patients who were operated was from 21 days to 9 months. None of the patients had symptoms, except one patient who had a large cyst and was vomiting. Prenatal ultrasound examination indicated an intra-abdominal cyst in all patients, but auto-amputated ovary diagnosis was not made. Differential postnatal diagnoses included an ovarian cyst, ovarian teratoma, tuba-ovarian torsion, mesenteric lymphatic malformation, and intestinal duplication cyst. Only one patient had an auto-amputated ovary suspicion in computed tomography. Laparoscopic exploration (n: 7) or laparotomy (n: 1) was performed. Histopathologic examination was necrosis and calcification (n: 6), necrosis (n: 1), and serous cystadenoma and necrosis (n: 1). Conclusion We suggest that laparoscopy should be used for diagnosis and treatment of antenatal intra-abdominal cysts that persist postnatally because of diagnostic dilemmas. We recommend in patients diagnosed with auto-amputated ovary that the other ovary should be carefully monitored and followed up in terms of ovarian cyst, due to the possible risk of torsion.
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    Publication
    Low-grade injury following testicular torsion: A multicenter study confirming a disturbing possibility
    (Karger, 2023-12-01) Çiğsar Kuzu, Emine Burcu; Tiryaki, Sibel; Güney, Neslihan; Polatdemir, Kamer; Çakır, Yasemin; Karagözlu Akgül, Ahsen; Toper, Muhammed Hasan; Karaguzel, Güngör; Uçar, Murat; Başsorgun, Cumhur İbrahim; Özel, Seyhmus Kerem; Özkanli, Şeyma; Salcı, Gül; Aydın Mungan, Sevdegül; Yılmaz, Mehmet Uğur; Aytaç Vuruşkan, Berna; Yagmur, Ismail; Tarini, Emine Zeynep; Kaba, Meltem; Tanik, Canan; Canbaz, Furkan Adem; Hurdogan, Ozge; User, Idil Rana; Orhan, Diclehan; Atici, Ahmet; Gursoy, Didar; Yagmurlu, Emin Aydin; Enneli, Duygu; Kilic, Seref Selcuk; Erdogan, Seyda; YILMAZ, MEHMET UĞUR; AYTAÇ VURUŞKAN, BERNA; Tıp Fakültesi; Patoloji Ana Bilim Dalı; GRA-7433-2022; EEJ-1452-2022
    Introduction: There is an ongoing debate whether to perform orchiectomy or orchidopexy following testicular torsion (TT) in cases where the testis seems non-viable. The main problem is lack of objective criteria defining testicular viability. The aim of this study was to investigate the grade of injury in orchiectomy specimens obtained from cases of TT and its association with clinical findings. Methods: This multicenter retrospective study involved double-blinded reassessment of the patient files and the pathological specimens using Mikuz classification to analyze the relation between clinical and pathological findings. Results: A total of 289 patient charts from 14 centers were reviewed and 228 were included in this study. Twenty (8.8%) patients had grade 1 injury which refers to reversible injury. The clinical findings of these 20 patients were compared to 208 patients with higher grades of injury. As expected, there was statistically significant difference regarding duration of symptoms (p < 0.001); however, range was wide in both groups (as long as 96 h for grade 1 and as short as 7 h for higher grades). There was no statistically significant difference in any other variable including age (median 14 for both, p = 0.531), symptoms (pain: 19/20 vs. 189/202, p = 0.801; swelling: 13/19 vs. 168/197, p = 0.094), absence of blood flow in Doppler US (15/19 vs. 164/197, p = 0.635), or degree of torsion (median 720(degrees )for both, p = 0.172). Conclusion: Our study revealed necessity for better criteria to define viability of testis following TT. Histopathological injury appeared to be reversible even in some patients with more severe perioperative findings, late admission, or high degree of twisting. Our findings support the tendency for testicular fixation instead of orchiectomy as none of the clinical or perioperative findings could be attributed to high-grade injury.