Publication: Levels of ischemia: Modified albumin in patients undergoing on-pump coronary artery bypass
dc.contributor.author | Özsin, Kadir Kaan | |
dc.contributor.author | Balcı, Abdullah Burak | |
dc.contributor.author | Sanri, Umut Serhat | |
dc.contributor.author | Yavuz, Şenol | |
dc.contributor.buuauthor | Güvenç, Orhan | |
dc.contributor.buuauthor | GÜVENÇ, ORHAN | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı. | |
dc.contributor.researcherid | ACJ-3462-2022 | |
dc.date.accessioned | 2024-07-09T07:15:11Z | |
dc.date.available | 2024-07-09T07:15:11Z | |
dc.date.issued | 2020-06-01 | |
dc.description.abstract | Objective: To investigate the effect of ischemia-modified albumin (IMA) during cardiopulmonary bypass (CPB).Study Design: Observational study.Place and Duration of Study: Department of Cardiovascular Surgery, Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey, between January and April 2018.Methodology: Patients, who underwent on-pump coronary bypass surgery, were inducted. IMA levels were measured in the preoperative period (IMA-T-1), 30 minutes after removal of aortic X-clamp (IMA-T-2) (ischemic period) and 6th hours (IMA-T-3) after surgery. The groups were formed according to the average value of IMA-T-2 levels measured in the ischemic period. Those with a value above the mean (0.76 U/mL) were grouped as group 1 and those below the mean were grouped as group 2. Postoperative data of the patients were recorded.Results: There were significant differences between measured IMA levels in different periods of on-pump CABG (p <0.001). The development of postoperative atrial fibrillation (PoAF) was higher in Group 1 and this result was statistically significant (p=0.004). High IMA-T2 levels were detected as an independent parameter in predicting the PoAF development (p=0.04, logistic regression analysis). ROC curve analysis demonstrated IMA-T2 values of 0.73 or above could predict development PoAF with 82.6% sensitivity and 66.7% specificity (AUC: 0.777, log rank p=0.001).Conclusion: Increased IMA levels during ischemic period may be predictive in PoAF development. | |
dc.identifier.doi | 10.29271/jcpsp.2020.6.561 | |
dc.identifier.endpage | 567 | |
dc.identifier.issn | 1022-386X | |
dc.identifier.issue | 6 | |
dc.identifier.startpage | 561 | |
dc.identifier.uri | https://doi.org/10.29271/jcpsp.2020.6.561 | |
dc.identifier.uri | https://hdl.handle.net/11452/43065 | |
dc.identifier.volume | 30 | |
dc.identifier.wos | 000552142000002 | |
dc.indexed.wos | WOS.SCI | |
dc.language.iso | en | |
dc.publisher | Coll Physicians & Surgeons Pakistan | |
dc.relation.journal | Jcpsp-journal Of The College Of Physicians And Surgeons Pakistan | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/closedAccess | |
dc.subject | Inflammatory response | |
dc.subject | Atrial-fibrillation | |
dc.subject | Surgery | |
dc.subject | Binding | |
dc.subject | Stress | |
dc.subject | Cardiopulmonary bypass | |
dc.subject | Myocardial ischemia | |
dc.subject | Ischemia-modified albumin | |
dc.subject | Science & technology | |
dc.subject | Life sciences & biomedicine | |
dc.subject | Medicine, general & internal | |
dc.subject | General & internal medicine | |
dc.title | Levels of ischemia: Modified albumin in patients undergoing on-pump coronary artery bypass | |
dc.type | Article | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 755f85da-5e61-4010-b12a-f429b34f1b4c | |
relation.isAuthorOfPublication.latestForDiscovery | 755f85da-5e61-4010-b12a-f429b34f1b4c |