Publication:
Transnasal transsphenoidal surgical method in pediatric pituitary adenomas

dc.contributor.buuauthorTaşkapılıoğlu, Mevlüt Özgür
dc.contributor.buuauthorYılmazlar, Selçuk
dc.contributor.buuauthorEren, Erdal
dc.contributor.buuauthorTarım, Ömer Faruk
dc.contributor.buuauthorGüler, Tuğba Moralı
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentEndokrinoloji Ana Bilim Dalı
dc.contributor.departmentNöroşirürji Ana Bilim Dalı
dc.contributor.orcid0000-0001-5472-9065
dc.contributor.orcid0000-0003-3633-7919
dc.contributor.orcid0000-0002-1684-1053
dc.contributor.researcheridAAW-5254-2020
dc.contributor.researcheridAAH-5070-2021
dc.contributor.researcheridJPK-3909-2023
dc.contributor.researcheridCCU-8073-2022
dc.contributor.researcheridHPH-3049-2023
dc.contributor.scopusid25936798300
dc.contributor.scopusid6603059483
dc.contributor.scopusid36113153400
dc.contributor.scopusid6701427186
dc.contributor.scopusid56729201700
dc.date.accessioned2024-05-22T08:33:23Z
dc.date.available2024-05-22T08:33:23Z
dc.date.issued2014
dc.description.abstractAim: To evaluate the clinical outcome in a 13-year consecutive series of children operated for pituitary adenomas with transnasal transsphenoidal surgery. Methods: All patients < 18 years who were operated on at our center by transsphenoidal surgery for pediatric pituitary adenomas were included in the study. Clinical features, hormonal profile, radiology, surgical approach, results and complications were analyzed. Results: Eighteen patients (90%) had functional pituitary adenomas and 2 (10%) patients had nonfunctional pituitary adenoma. The most common type was prolactin-secreting adenoma (n = 12), followed by corticotropinoma (n = 4), growth hormone-secreting adenoma (n = 2), and nonfunctioning adenoma (n = 2). Prolactin-secreting adenomas in children occurred more commonly with suprasellar expansion than did other adenomas. Conclusion: Transsphenoidal surgery was effective for decompression of suprasellar extension and relieved the chiasmal compression immediately. Prolactin-secreting tumors required postoperative medical therapy for persistently elevated prolactin levels.
dc.identifier.doihttps://doi.org/10.1159/000381862
dc.identifier.endpage132
dc.identifier.issn1016-2291
dc.identifier.issn1423-0305
dc.identifier.issue3
dc.identifier.pubmed25997786
dc.identifier.scopus2-s2.0-84937519360
dc.identifier.startpage128
dc.identifier.urihttps://karger.com/pne/article/50/3/128/277249/Transnasal-Transsphenoidal-Surgical-Method-in
dc.identifier.urihttps://hdl.handle.net/11452/41514
dc.identifier.volume50
dc.identifier.wos000357861100003
dc.indexed.pubmedPubMed
dc.indexed.scopusScopus
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherKarger
dc.relation.journalPediatric Neurosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPituitary adenomas
dc.subjectTranssphenoidal surgery
dc.subjectProlactinoma
dc.subject.emtreeActh secreting adenoma
dc.subject.emtreeAdenoma
dc.subject.emtreeAdolescent
dc.subject.emtreeArticle
dc.subject.emtreeChild
dc.subject.emtreeChildhood disease
dc.subject.emtreeClinical article
dc.subject.emtreeFemale
dc.subject.emtreeFollow up
dc.subject.emtreeGrowth hormone secreting adenoma
dc.subject.emtreeHormone substitution
dc.subject.emtreeHuman
dc.subject.emtreeHypophysis adenoma
dc.subject.emtreeHypopituitarism
dc.subject.emtreeMale
dc.subject.emtreeMicroadenoma
dc.subject.emtreeNeuroimaging
dc.subject.emtreePriority journal
dc.subject.emtreeProlactin blood level
dc.subject.emtreeProlactinoma
dc.subject.emtreeRetrospective study
dc.subject.emtreeSchool child
dc.subject.emtreeTranssphenoidal surgery
dc.subject.emtreeTreatment outcome
dc.subject.emtreeTumor recurrence
dc.subject.emtreeVisual field defect
dc.subject.emtreeAdenoma
dc.subject.emtreeNeurosurgery
dc.subject.emtreeNose cavity
dc.subject.emtreePituitary neoplasms
dc.subject.emtreeProcedures
dc.subject.emtreeSphenoid sinüs
dc.subject.emtreeProlactin
dc.subject.emtreeProlactin
dc.subject.emtreeProlactin
dc.subject.meshAdenoma
dc.subject.meshAdolescent
dc.subject.meshChild
dc.subject.meshFemale
dc.subject.meshFollow-up studies
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshNasal cavity
dc.subject.meshNeurosurgical procedures
dc.subject.meshPituitary neoplasms
dc.subject.meshRetrospective studies
dc.subject.meshSphenoid sinus
dc.subject.scopusProlactinoma; Pituitary Neoplasms; Dopamine Receptor Stimulating Agent
dc.subject.wosClinical neurology
dc.subject.wosSurgery
dc.subject.wosPediatrics
dc.titleTransnasal transsphenoidal surgical method in pediatric pituitary adenomas
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Nöroşirürji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Endokrinoloji Ana Bilim Dalı
local.indexed.atWOS

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