Serum antioxidant capacity and oxidative damage in clinical and subclinical canine ehrlichiosis
dc.contributor.author | Rubio, Camila Peres | |
dc.contributor.author | Martínez, Silvia Subiela | |
dc.contributor.author | Hernández, Josefa Ruiz | |
dc.contributor.author | Tvarijonaviciute, Asta | |
dc.contributor.author | Escribano, Damián | |
dc.contributor.author | Ceron, Jose Joaquín | |
dc.contributor.buuauthor | Yılmaz, Zeki | |
dc.contributor.buuauthor | Kocatürk, Meriç | |
dc.contributor.buuauthor | Yalçın, Ebru | |
dc.contributor.department | Uludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0001-9836-0749 | tr_TR |
dc.contributor.researcherid | V-5578-2017 | tr_TR |
dc.contributor.scopusid | 35944810500 | tr_TR |
dc.contributor.scopusid | 36437200800 | tr_TR |
dc.contributor.scopusid | 36778554000 | tr_TR |
dc.date.accessioned | 2023-01-13T08:02:03Z | |
dc.date.available | 2023-01-13T08:02:03Z | |
dc.date.issued | 2017-06-10 | |
dc.description.abstract | The objective of this study was to evaluate and compare the antioxidant response and the products of oxidative damage analysed by various assays in clinical and subclinical canine monocytic ehrlichiosis (CME). For this purpose, four assays to measure the total serum antioxidant capacity (TAC), such as the cupric reducing antioxidant capacity (CUPRAC), ferric reducing ability of plasma (FRAP), trolox equivalent antioxidant capacity (TEAC) using acidic medium (TEAC(A)), and the TEAC using the horseradish peroxidase (TEAC(H)) were used. In addition, the serum thiol concentrations were analysed. Reactive oxygen species (ROS), thiobarbituric acid reactive substances (TBARS), and ferrous oxidation-xylenol orange (FOX) were measured to determine the concentrations of free radical and the products of oxidative damage as result of the disease. All antioxidant markers were significantly lower in the dogs on clinical ehrlichiosis when compared with healthy dogs; however only the CUPRAC, FRAP and thiol were significantly lower in subclinical CME compared with healthy dogs. TBARS and FOX showed no significant differences between dogs with CME and healthy dogs; however, a significant increased ROS concentration was observed in dogs with clinical and subclinical CME when compared with healthy dogs. Results showed that in CME there is a state of oxidative stress with significant changes in markers of antioxidant defence and in concentrations of free radicals. However, the detection of these changes would depend of the assay used. | en_US |
dc.description.sponsorship | Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) - 200568/2014-0 | en_US |
dc.description.sponsorship | Ministerio de Economia y Competitividad of Spain | en_US |
dc.description.sponsorship | Fundacion Seneca - 19,894/GERM/15 | en_US |
dc.identifier.citation | Rubio, C. P. vd. (2017). ''Serum antioxidant capacity and oxidative damage in clinical and subclinical canine ehrlichiosis''. Research in Veterinary Science, 115, 301-306. | en_US |
dc.identifier.endpage | 306 | tr_TR |
dc.identifier.issn | 0034-5288 | |
dc.identifier.pubmed | 28628845 | tr_TR |
dc.identifier.scopus | 2-s2.0-85020804814 | tr_TR |
dc.identifier.startpage | 301 | tr_TR |
dc.identifier.uri | https://doi.org/10.1016/j.rvsc.2017.06.004 | |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0034528817300838 | |
dc.identifier.uri | 1532-2661 | |
dc.identifier.uri | http://hdl.handle.net/11452/30445 | |
dc.identifier.volume | 115 | tr_TR |
dc.identifier.wos | 000418308700043 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.collaboration | Yurt dışı | tr_TR |
dc.relation.journal | Research in Veterinary Science | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.relation.tubitak | TOVAG-213O032 | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Veterinary sciences | en_US |
dc.subject | CUPRAC | en_US |
dc.subject | Ehrlichiosis | en_US |
dc.subject | Fox | en_US |
dc.subject | Frap | en_US |
dc.subject | ROS | en_US |
dc.subject | Thiol | en_US |
dc.subject | Acute-phase proteİn | en_US |
dc.subject | Monocytİc ehrlİchİosİs | en_US |
dc.subject | Dogs | en_US |
dc.subject | Plasma | en_US |
dc.subject | Stress | en_US |
dc.subject | Dİsease | en_US |
dc.subject | Thİols | en_US |
dc.subject | Acİd | en_US |
dc.subject | Valİdatİon | en_US |
dc.subject | Assay | en_US |
dc.subject.emtree | Antioxidant | en_US |
dc.subject.emtree | Biological marker | en_US |
dc.subject.emtree | C reactive protein | en_US |
dc.subject.emtree | Chloroxylenol | en_US |
dc.subject.emtree | Ferritin | en_US |
dc.subject.emtree | Ferrous chloride | en_US |
dc.subject.emtree | Ferrous oxidation xylenol orange | en_US |
dc.subject.emtree | Free radical | en_US |
dc.subject.emtree | Horseradish peroxidase | en_US |
dc.subject.emtree | Reactive oxygen metabolite | en_US |
dc.subject.emtree | Reagent | en_US |
dc.subject.emtree | Thiobarbituric acid reactive substance | en_US |
dc.subject.emtree | Thiol | en_US |
dc.subject.emtree | Unclassified drug | en_US |
dc.subject.emtree | Antioxidant | en_US |
dc.subject.emtree | Analytical parameters | en_US |
dc.subject.emtree | Antioxidant assay | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Asymptomatic infection | en_US |
dc.subject.emtree | Biochemical analysis | en_US |
dc.subject.emtree | Blood level | en_US |
dc.subject.emtree | Canine ehrlichiosis | en_US |
dc.subject.emtree | Canine monocytic ehrlichiosis | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Correlational study | en_US |
dc.subject.emtree | Cupric reducing antioxidant capacity assay | en_US |
dc.subject.emtree | Ferric reducing antioxidant power assay | en_US |
dc.subject.emtree | Inflammation | en_US |
dc.subject.emtree | Nonhuman | en_US |
dc.subject.emtree | Cxidative stress | en_US |
dc.subject.emtree | Thiol blood level | en_US |
dc.subject.emtree | Total serum antioxidant capacity | en_US |
dc.subject.emtree | Trolox equivalent antioxidant capacity assay | en_US |
dc.subject.emtree | Animal | en_US |
dc.subject.emtree | Asymptomatic infection | en_US |
dc.subject.emtree | Blood | en_US |
dc.subject.emtree | Blood analysis | en_US |
dc.subject.emtree | Comparative study | en_US |
dc.subject.emtree | Dog | en_US |
dc.subject.emtree | Dog disease | en_US |
dc.subject.emtree | Ehrlichiosis | en_US |
dc.subject.emtree | Parasitology | en_US |
dc.subject.emtree | Procedures | en_US |
dc.subject.emtree | Veterinary | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Antioxidants | en_US |
dc.subject.mesh | Asymptomatic infections | en_US |
dc.subject.mesh | Blood chemical analysis | en_US |
dc.subject.mesh | Dog diseases | en_US |
dc.subject.mesh | Dogs | en_US |
dc.subject.mesh | Oxidative stress | en_US |
dc.subject.mesh | Ehrlichiosis | en_US |
dc.subject.scopus | Ehrlichia Canis; Animals; Babesia Canis Subsp. Vogeli | en_US |
dc.subject.wos | Veterinary sciences | en_US |
dc.title | Serum antioxidant capacity and oxidative damage in clinical and subclinical canine ehrlichiosis | en_US |
dc.type | Article | |
dc.wos.quartile | Q1 | en_US |
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